Medicine Overview

Indication

Know Medicine, Follow Guideline

Adult Dose

Clinical InformationAdministration Information
Age: Adults (including elderly patients)
Dose: Oral – 250-500mg
Frequency: 3-4 times a day
Age: Adults (including elderly patients)
Dose: Intravenous – 0.25-1 g
Frequency: 4 times/day
Note: may double in severe cases

Child Dose

Clinical InformationAdministration Information
Age: Children
Dose: Form – 12.5-25 mg/kg body weight
Frequency: four times daily
Age: 2-10 years
Condition: Intravenous
Dose: Form – Half of adult dose

Renal Dose

Clinical InformationAdministration Information
Condition: Renal impairment with creatinine clearance less than 10 milliliters per minute
Dose: Dosage Form - Not specified
Note: Dosage adjustment may be necessary
Administration
  • Take on empty stomach
  • Take 30-60 minutes before meals
Side Effect

Drug Interaction

Drug NameRisk Factors
Methotrexate
May increase risk of toxicity
Oestrogen-containing oral contraceptives
May decrease efficacy

Disease Interaction

Disease NameRisk Factors
Porphyria
Can trigger acute attacks

Pregnancy

Lactation
Special Use
Precaution
Overdose
Pharmacology
Storage
Keep in a dry place away from light and heat. Keep out of the reach of children.

Data Sources

Clinical & regulatory information on this page is compiled from the following government sources:

DISCLAIMER: This drug information content is provided for informational purposes only and is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Patients should always consult their physician with any questions regarding a medical condition and to obtain medical advice and treatment.