Medicine Overview
Adult Dose
| Clinical Information | Administration Information |
|---|---|
|
Indication: Ankylosing spondylitis; Osteoarthritis; Rheumatoid arthritis Age: Adult |
Dose: Oral – 150 mg Frequency: twice daily Note: may adjust subsequent doses based on response. Max: 400 mg/day. |
|
Indication: Acute painful shoulder Age: Adult |
Dose: Oral – 200 mg Frequency: twice daily Duration: 7-14 days is usually adequate Note: may reduce dose after satisfactory response achieved. Max: 400 mg/day. |
Child Dose
| Clinical Information | Administration Information |
|---|---|
|
Age: Pediatric |
Dose: Safety & efficacy not established Note: Safety and efficacy not established |
Renal Dose
| Clinical Information | Administration Information |
|---|---|
|
Condition: Renal impairment |
Dose: Not mentioned – Not mentioned Note: May need dosage reduction. Not recommended in severe renal impairment. |
Administration
- Take with food
- Take after meals
Side Effect
- GI pain (10%)
- Constipation (3-9%)
- Diarrhea (3-9%)
- Dizziness (3-9%)
- Dyspepsia (3-9%)
- Headache (3-9%)
- Nausea (3-9%)
- Rash (3-9%)
- Abdominal cramps (1-3%)
- Anorexia (1-3%)
- Edema (1-3%)
- Nervousness (1-3%)
- Pruritus (1-3%)
- Tinnitus (1-3%)
- Vomiting (1-3%)
- Hypersensitivity reactions
- Thrombocytopenia
- Ecchymosis
- Purpura
- Leukopenia
- Agranulocytosis
- Neutropenia
- Bone marrow depression
- CHF (Less than 1%)
- Hematuria (Less than 1%)
- Renal impairment (including renal failure)
- Interstitial nephritis
- Nephrotic syndrome
- Anaphylaxis reactions
- cross-sensitivity reactions in patients with known aspirin triad reactions
- Steven-Johnson Syndrome and toxic epidermal necrolysis
Drug Interaction
Drug Interaction
| Drug Name | Risk Factors |
|---|---|
|
Dimethyl sulfoxide
|
May result in peripheral neuropathy
|
|
Ciclosporin
|
Increased nephrotoxicity
|
Disease Interaction
Disease Interaction
| Disease Name | Risk Factors |
|---|---|
|
Peri-Operative Pain In CABG Surgery
|
Risk of bleeding complications
|
Pregnancy
Pregnancy
Lactation
Special Use
Precaution
Overdose
Pharmacology
Storage
Keep below 25°C temperature, away from light & moisture. Keep out of the reach of children.
Data Sources
Clinical & regulatory information on this page is compiled from the following government sources:
DISCLAIMER: This drug information content is provided for informational purposes only and is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Patients should always consult their physician with any questions regarding a medical condition and to obtain medical advice and treatment.