Medicine Overview
Adult Dose
| Clinical Information | Administration Information |
|---|---|
|
Indication: Pancreatic insufficiency Age: Adult |
Dose: Tablet – 1-3 tablets Frequency: daily Note: by mouth with meal |
Child Dose
| Clinical Information | Administration Information |
|---|---|
|
Indication: Exocrine pancreatic insufficiency due to cystic fibrosis or other conditions Age: Infants (up to 12 months) |
Dose: Oral – 2,000 to 4,000 lipase units per 120 mL of formula or per breastfeeding Note: by mouth (oral) |
|
Indication: Exocrine pancreatic insufficiency due to cystic fibrosis or other conditions Age: 12 months to less than 4 years |
Dose: Oral – 1,000 lipase units/kg Frequency: With every meal; half dose with each snack Note: by mouth (oral) |
Administration
- Take with meals
- Swallow whole, do not crush
Side Effect
- GI effects eg abdominal discomfort
- nausea and vomiting
- Buccal and perianal irritation
- particularly in infants
- Colonic strictures may occur
- mainly in children with cystic fibrosis receiving high doses of pancreatin preparations
- Hyperuricaemia and hyperuricosuria may occur
Drug Interaction
Drug Interaction
| Drug Name | Risk Factors |
|---|---|
|
Folic acid
|
May impair oral absorption when taken together
|
|
Acarbose
|
Antagonises hypoglycaemic effect
|
Disease Interaction
Disease Interaction
| Disease Name | Risk Factors |
|---|---|
|
Acute Pancreatitis
|
Can worsen inflammation
|
|
Acute Pancreatic Disease
|
May aggravate condition
|
Pregnancy
Pregnancy
Lactation
Special Use
Precaution
Overdose
Pharmacology
Storage
Keep all medicines out of reach of children. Store in a cool and dry place, protected from light.
Data Sources
Clinical & regulatory information on this page is compiled from the following government sources:
DISCLAIMER: This drug information content is provided for informational purposes only and is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Patients should always consult their physician with any questions regarding a medical condition and to obtain medical advice and treatment.