Medicine Overview
Adult Dose
| Clinical Information | Administration Information |
|---|---|
|
Indication: Susceptible infections Age: Adult |
Dose: Oral – 250-500 mg Frequency: every 6 hours Note: Maximum: 4 g/day |
|
Indication: Acne Age: Adult |
Dose: Oral – 250-500 mg Frequency: daily, in divided doses Duration: for at least 3 months |
Child Dose
| Clinical Information | Administration Information |
|---|---|
|
Age: less than 8 years |
Dose: Oral – Not recommended |
|
Age: greater than 8 years |
Dose: Oral – 25–50 mg/kg/day Frequency: every 6 hours Note: not to exceed 3 g/day |
Renal Dose
| Clinical Information | Administration Information |
|---|---|
|
Condition: Renal impairment Creatinine Clearance 50-80 mL/min |
Dose: Not specified Frequency: every 8-12 hours |
|
Condition: Renal impairment Creatinine Clearance 10-50 mL/min |
Dose: Not specified Frequency: every 12-24 hours |
Administration
- Take on empty stomach
- Take 1 hour before or 2 hours after meals
Side Effect
- Discoloration of teeth and enamel hypoplasia (young children)
- Diarrhea
- Nausea
- Photosensitivity
- Anorexia
- Abdominal cramps
- Antibiotic-associated pseudomembranous colitis
- Bulging fontanels in infants
- Diabetes insipidus syndrome
- Esophagitis
- Exfoliative dermatitis
- Incr ICP
- Pericarditis
- Pseudotumor cerebri
- Pancreatitis
- Pruritus
- Pigmentation of nails
- Vomiting
- Anaphylaxis
- hepatotoxicity
- nephrotoxicity
- blood dyscrasias
Drug Interaction
Drug Interaction
| Drug Name | Risk Factors |
|---|---|
|
Antacids containing divalent and trivalent cations (e.g. Al, Ca, Mg), Fe, Zn and Na bicarbonate preparations, kaolin-pectin, bismuth subsalicylate, sucralfate, strontium ranelate, colestipol, colestyramine
|
Impaired absorption
|
|
Penicillin
|
May interfere with the bactericidal action
|
Disease Interaction
Disease Interaction
| Disease Name | Risk Factors |
|---|---|
|
Renal Impairment
|
Can worsen kidney function
|
Pregnancy
Pregnancy
Lactation
Special Use
Precaution
Overdose
Pharmacology
Storage
Store between 20-25° C.
Data Sources
Clinical & regulatory information on this page is compiled from the following government sources:
DISCLAIMER: This drug information content is provided for informational purposes only and is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Patients should always consult their physician with any questions regarding a medical condition and to obtain medical advice and treatment.