Medicine Overview

Indication

Know Medicine, Follow Guideline

Adult Dose

Clinical InformationAdministration Information
Indication: Minor dermatological procedures (e.g. intravenous cannulation or venipuncture)
Dose: Cream – 2.5 g
Duration: at least 1 hour
Note: Apply over 20-25 square centimeters of skin surface area.
Indication: Painful dermatological procedures involving large areas (e.g. split thickness skin graft harvesting)
Dose: Cream – 2 g / 10 square centimeters of skin
Duration: at least 2 hours
Note: Allow to remain in contact with the skin. Analgesia is achieved in 1 hour, reaches maximum in 2-3 hours, and persists 1-2 hours after removal.

Child Dose

Clinical InformationAdministration Information
Indication: Local Anesthetic Procedures
Age: Neonates (gestation age less than 37 weeks)
Dose: Cream
Note: Use not recommended
Indication: Local Anesthetic Procedures
Age: less than 12 months
Dose: Cream
Note: Do not use if receiving treatment with methemoglobinemia-inducing agents
Administration
  • Clean area first
  • Apply thick layer
Side Effect

Drug Interaction

Drug NameRisk Factors
Drugs that cause methaemoglobinaemia
Increased risk of toxicity
Class III Antiarrhythmics (Amiodarone, Flecainide, Propafenone, Quinidine, Disopyramide, Procainamide)
Additive cardiac effects

Disease Interaction

Disease NameRisk Factors
Application on mucous membranes
Risk of absorption toxicity
Broken or inflamed skin
Increased absorption risk

Pregnancy

Lactation
Special Use
Precaution
Overdose
Pharmacology
Storage
Store in a cool and dry place, protected from light

Data Sources

Clinical & regulatory information on this page is compiled from the following government sources:

DISCLAIMER: This drug information content is provided for informational purposes only and is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Patients should always consult their physician with any questions regarding a medical condition and to obtain medical advice and treatment.