Medicine Overview
Adult Dose
| Clinical Information | Administration Information |
|---|---|
|
Indication: Acute musculoskeletal disorders Age: Adult |
Dose: Oral – 20 mg Frequency: once daily Duration: Up to 7 days, up to 14 days for severe cases Note: Taken at the same time each day. Maximum: 40 mg/day (short term use). |
|
Indication: Osteoarthritis Age: Adult |
Dose: Oral – 20 mg Frequency: once daily Note: Taken at the same time each day. Maximum: 40 mg/day (short term use). |
Child Dose
| Clinical Information | Administration Information |
|---|---|
|
Age: Pediatric |
Dose: No approved pediatric dosage available Note: No approved pediatric dosage available |
Administration
- Take with food
- Take with or immediately after meals
Side Effect
- Dyspepsia
- nausea
- abdominal pain and discomfort
- constipation
- diarrhoea
- flatulence
- indigestion
- epigastric distress
- stomatitits
- anorexia
- peripheral oedema
- headache
- dizziness
- allergic reactions
- asthma
- bronchospasm
- dyspnoea
- rash
- pruritus
- decreased Hb
- anaemia
- thrombocytopenia
- non-thrombocytopenic purpura
- leucopenia
- eosinophilia
- epistaxis
- increased serum transaminase levels
- swollen eyes
- blurred vision
- eye irritation
- malaise
- tinnitus
- oedema
- HTN
- cardiac failure
- Peptic ulceration
- GI bleeding
- anaphylaxis
- Lyell's syndrome
- Stevens-Johnson syndrome
- exfoliative dermatitis
- nephrotoxicity
- arterial thrombotic events (eg MI or stroke)
- hepatitis
- jaundice
Drug Interaction
Drug Interaction
| Drug Name | Risk Factors |
|---|---|
|
Salicylates, NSAIDs (Ibuprofen, Naproxen, Diclofenac, Celecoxib, Meloxicam, Indomethacin, Piroxicam, Ketorolac)
|
Increased risk of adverse effects (particularly GI)
|
|
Warfarin, other Anticoagulants (Warfarin, Heparin, Dabigatran, Rivaroxaban, Apixaban, Edoxaban)
|
May enhance the anticoagulant effect
|
Disease Interaction
Disease Interaction
| Disease Name | Risk Factors |
|---|---|
|
Active GI Bleed/Peptic Ulcer
|
Risk of severe bleeding
|
|
Severe Heart Failure
|
Can worsen heart condition
|
Pregnancy
Pregnancy
Lactation
Special Use
Precaution
Overdose
Pharmacology
Storage
Do not store above 30°C, protect from light & moisture. Keep out of the reach of children.
Data Sources
Clinical & regulatory information on this page is compiled from the following government sources:
DISCLAIMER: This drug information content is provided for informational purposes only and is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Patients should always consult their physician with any questions regarding a medical condition and to obtain medical advice and treatment.