Medicine Overview
Adult Dose
| Clinical Information | Administration Information |
|---|---|
|
Indication: Prophylaxis of thrombotic stroke Age: Adult: greater than 18 years |
Dose: Oral – 250 mg Frequency: twice daily Note: Hepatic impairment: Severe: contraindicated |
|
Indication: Ischaemic heart disease Age: Adult: greater than 18 years |
Dose: Oral – 250 mg Frequency: twice daily Note: Hepatic impairment: Severe: contraindicated |
Child Dose
| Clinical Information | Administration Information |
|---|---|
|
Age: less than 18 years old |
Dose: Not established Note: Safety and efficacy not established |
Renal Dose
| Clinical Information | Administration Information |
|---|---|
|
Condition: Renal impairment |
Dose: Dose: Note: Dose reduction or discontinuance if haemorrhagic or haematopoietic complications occur. |
Administration
- Take with food
- Take with meals
Side Effect
- Diarrhea (12.5%)
- Elevated alkaline phosphatase (7.6%)
- Nausea (7%)
- Dyspepsia (7%)
- Rash (5%)
- GI pain (3.7%)
- Elevated AST/SGOT (3.1%)
- Neutropenia (2.4%)
- Purpura (2.2%)
- Vomiting (1.9%)
- Flatulence (1.5%)
- Pruritus (1.3%)
- Dizziness (1%)
- Abnormal LFTs (1%)
- Anorexia (1%)
- Agranulocytosis
- Aplastic anemia
- Pancytopenia
- TTP
- Neutropenia
- agranulocytosis
- thrombotic thrombocytopenic purpura and aplastic anaemia
Drug Interaction
Drug Interaction
| Drug Name | Risk Factors |
|---|---|
|
Cimetidine
|
Reduced clearance
|
|
Corticosteroids (Prednisone, Prednisolone, Methylprednisolone, Dexamethasone, Hydrocortisone)
|
May antagonise effects on bleeding time
|
Disease Interaction
Disease Interaction
| Disease Name | Risk Factors |
|---|---|
|
Blood Dyscrasias
|
Can worsen blood disorders
|
|
Active Bleeding/Bleeding Disorders
|
Risk of severe bleeding
|
Pregnancy
Pregnancy
Lactation
Special Use
Precaution
Overdose
Pharmacology
Storage
Store at 15° to 30° C
Data Sources
Clinical & regulatory information on this page is compiled from the following government sources:
DISCLAIMER: This drug information content is provided for informational purposes only and is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Patients should always consult their physician with any questions regarding a medical condition and to obtain medical advice and treatment.