Medicine Overview
Adult Dose
| Clinical Information | Administration Information |
|---|---|
|
Age: Adults |
Dose: Intravenous infusion – Initial dose of 100 mg, followed by 50 mg Frequency: every 12 hours Note: Intravenous infusions should be administered over approximately 30 to 60 minutes every 12 hours. The duration of therapy should be guided by the severity and site of the infection and the patient's clinical and bacteriological progress. |
|
Indication: Complicated skin and skin structure infections Age: Adults |
Dose: Intravenous infusion – Initial dose of 100 mg, followed by 50 mg Frequency: every 12 hours Duration: 5 to 14 days Note: Intravenous infusions should be administered over approximately 30 to 60 minutes every 12 hours. |
Child Dose
| Clinical Information | Administration Information |
|---|---|
|
Age: Pediatric |
Dose: No approved pediatric dosage available Note: No approved pediatric dosage available |
Renal Dose
| Clinical Information | Administration Information |
|---|---|
|
Condition: Renal impairment |
Dose: Not mentioned – No dosage adjustment needed. Note: Renal impairment: No dosage adjustment needed. |
Administration
- Must be administered by healthcare professional
- Infuse over 30-60 minutes
Side Effect
- Nausea (29.5%)
- Vomiting (19.7%)
- Diarrhea (12.7%)
- Infection (8.3%)
- Fever (7.1%)
- Abd pain (6.8%)
- Headache (5.9%)
- HTN (4.9%)
- Anemia (4.2%)
- Dizziness (3.5%)
- Dyspnea (2.9%)
- Pruritus (2.6%)
- Rash (2.4%)
- Hypotension (2.3%)
- Insomnia (2.3%)
Drug Interaction
Drug Interaction
| Drug Name | Risk Factors |
|---|---|
|
Warfarin
|
Increased serum levels
|
|
Oral contraceptives
|
May decrease efficacy
|
Disease Interaction
Disease Interaction
| Disease Name | Risk Factors |
|---|---|
|
Hypersensitivity
|
Severe allergic reactions
|
|
Hospital-Acquired Pneumonia
|
Not effective for treatment
|
Pregnancy
Pregnancy
Lactation
Special Use
Precaution
Overdose
Pharmacology
Storage
Prior to reconstitution, Tigecycline should be stored at 20°C to 25°C. Once reconstituted, Tigecycline may be stored at room temperature for up to 24 hours (up to 6 hours in the vial and the remaining time in the intravenous bag). Reconstituted solution may be stored refrigerated at 2°C to 8°C for up to 48 hours following immediate transfer of reconstituted solution into the intravenous bag.
Data Sources
Clinical & regulatory information on this page is compiled from the following government sources:
DISCLAIMER: This drug information content is provided for informational purposes only and is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Patients should always consult their physician with any questions regarding a medical condition and to obtain medical advice and treatment.