Medicine Overview

Indication

Know Medicine, Follow Guideline

Adult Dose

Clinical InformationAdministration Information
Indication: Hypertension
Age: Adult
Condition: Immediate release
Dose: Oral – 80 mg
Frequency: initially every 8 hours
Note: maintenance: 80-320 mg by mouth every 12 hours
Indication: Hypertension
Age: Adult
Condition: Extended release
Dose: Oral – 180 mg per day
Note: 120 mg per day initially if patient elderly or of small stature; for desired response, may be increased to 240 mg per day by mouth, then by 120 mg per day at weekly intervals; not to exceed 480 mg per day

Child Dose

Clinical InformationAdministration Information
Indication: Supraventricular Tachycardia
Age: 1-15 years old
Dose: Intravenous – 0.1-0.3 mg/kg
Duration: over 2 minutes
Note: not to exceed 5 mg; second dose (not to exceed 10 mg) may be given after 30 minutes
Indication: Supraventricular Tachycardia
Age: 1-15 years old
Dose: Oral – 4-8 mg/kg/day
Frequency: divided every 8 hours
Note: by mouth (oral); not well established

Renal Dose

Clinical InformationAdministration Information
Condition: Renal impairment
Dose: Tablet/Capsule, extended release – 100 mg
Frequency: once daily at bedtime
Note: For Verelan PM, manufacturer recommends 100 mg at bedtime initially; use with caution and monitor electrocardiogram
Condition: Renal impairment with Creatinine Clearance less than 10 mL/minute
Dose: Tablet/Capsule, extended release – Dosage reduced by 25-50%
Note: Use with caution and monitor electrocardiogram
Administration
  • Should be taken with food
  • Take at regular intervals
Side Effect

Drug Interaction

Drug NameRisk Factors
Beta-blockers (Propranolol, Metoprolol, Atenolol, Bisoprolol, Carvedilol, Nadolol, Timolol, Sotalol), flecainide
Increased cardiac depressant effects
Digoxin
Increased risk of additive bradycardia, conduction disturbances and digoxin toxicity

Disease Interaction

Disease NameRisk Factors
Cardiogenic Shock
Can worsen heart failure
Hypotension
Can dangerously lower blood pressure

Pregnancy

Lactation
Special Use
Precaution
Overdose
Pharmacology
Storage
Do not store above 30°C. Keep away from light and out of the reach of children.

Data Sources

Clinical & regulatory information on this page is compiled from the following government sources:

DISCLAIMER: This drug information content is provided for informational purposes only and is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Patients should always consult their physician with any questions regarding a medical condition and to obtain medical advice and treatment.