Medicine Overview
Adult Dose
| Clinical Information | Administration Information |
|---|---|
|
Indication: Acute Herpes Zoster (Shingles) Age: Adults Condition: Immunocompetent |
Dose: Tablet – 500 mg Frequency: by mouth every 8 hours Duration: 7 days Note: Initiated within 72 hours of symptom or lesion onset |
|
Indication: Herpes Labialis Age: Adults Condition: Immunocompetent, Initial episode |
Dose: Tablet – 250 mg Frequency: by mouth every 8 hours Duration: 7-10 days |
Child Dose
| Clinical Information | Administration Information |
|---|---|
|
Age: Child |
Dose: Tablet – No approved pediatric dosage available Note: No approved pediatric dosage available |
Renal Dose
| Clinical Information | Administration Information |
|---|---|
|
Indication: Acute herpes zoster Condition: Creatinine clearance greater than 60 mL/min |
Dose: Tablet – Regular dosage Note: Regular dosage refers to standard dosing for patients with normal renal function |
|
Indication: Acute herpes zoster Condition: Creatinine clearance 40-59 mL/min |
Dose: Tablet – 500 mg Frequency: every 12 hours |
Administration
- Can be taken with or without food
- Take full course as prescribed
Side Effect
- Headache (23%)
- Nausea (13%)
- Diarrhea (2-9%)
- Abdominal pain (8%)
- Dysmenorrhea (Less than 8%)
- )
- Flatulence (5%)
- Pruritus (4%)
- Rash (3%)
- Paresthesia (3%)
- Neutropenia (3%)
- Increased transaminases (2-3%)
- Increased bilirubin (2%)
- Fatigue (1%)
- Arthralgia
- Confusion
- Dizziness
- Erythema multiforme
- Hallucinations
- Jaundice
- Rigors
- Thrombocytopenia
- Upper respiratory tract infection (URTI)
Drug Interaction
Drug Interaction
| Drug Name | Risk Factors |
|---|---|
|
Probenecid
|
Reduced renal excretion resulting in increased plasma concentration
|
|
Raloxifen
|
May reduce the formation of penciclovir, the active metabolite of famciclovir
|
Disease Interaction
Disease Interaction
| Disease Name | Risk Factors |
|---|---|
|
Data not available
|
Data not available
|
Pregnancy
Pregnancy
Lactation
Special Use
Precaution
Overdose
Pharmacology
Storage
Store at 20-25°C.
Data Sources
Clinical & regulatory information on this page is compiled from the following government sources:
DISCLAIMER: This drug information content is provided for informational purposes only and is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Patients should always consult their physician with any questions regarding a medical condition and to obtain medical advice and treatment.