Medicine Overview
Adult Dose
| Clinical Information | Administration Information |
|---|---|
|
Indication: Replacement therapy in primary immunodeficiency syndromes |
Dose: Injection – Starting dose: 0.4-0.8 g/kg Frequency: followed by 0.2-0.8 g/kg every 2-4 weeks Note: To achieve IgG trough level of 4.6 g/L |
|
Indication: Replacement therapy in myeloma or chronic lymphotic leukaemia Condition: severe secondary hypogammaglobulinaemia and recurrent infections |
Dose: Injection – 0.2-0.4 g/kg Frequency: every 3-4 weeks |
Child Dose
| Clinical Information | Administration Information |
|---|---|
|
Indication: Primary immunodeficiency Age: 2 years and older |
Dose: Intravenous – 300 to 800 mg/kg Frequency: Every 3 to 4 weeks |
|
Indication: Chronic idiopathic thrombocytopenic purpura Age: Child |
Dose: Intravenous – 400 mg/kg Frequency: Daily Duration: 2 to 5 consecutive days |
Administration
- For IV use only
- Must be given slowly
Side Effect
- Headache
- cough
- Injection site reaction
- nausea
- pharyngitis & urticaria
- fatigue
- arthralgia & pyrexia
- vomiting
- fever
- back pain & rash
- chills
- HTN
- asthenia
Drug Interaction
Drug Interaction
| Drug Name | Risk Factors |
|---|---|
|
Live measles vaccine, live mumps vaccine, live rubella vaccine, live varicella vaccine
|
May interfere with the immune response; these vaccines should be given at least 3 wk before or 3 mth after the admin of the immunoglobulins
|
Disease Interaction
Disease Interaction
| Disease Name | Risk Factors |
|---|---|
|
Fructose intolerance
|
Metabolic complications
|
Pregnancy
Pregnancy
Lactation
Special Use
Precaution
Overdose
Pharmacology
Storage
Details coming soon
Data Sources
Clinical & regulatory information on this page is compiled from the following government sources:
DISCLAIMER: This drug information content is provided for informational purposes only and is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Patients should always consult their physician with any questions regarding a medical condition and to obtain medical advice and treatment.