Medicine Overview
Adult Dose
| Clinical Information | Administration Information |
|---|---|
|
Indication: Advanced Prostate Cancer |
Dose: Subcutaneous Injection – 1 mg (0.2 mL) Frequency: single daily |
|
Indication: Endometriosis |
Dose: Intramuscular Injection – 3.75 mg Frequency: monthly Duration: up to 6 months Note: Recommended duration of treatment is 6 months; may treat again for additional 6 months, but with concomitant administration of norethindrone |
Child Dose
| Clinical Information | Administration Information |
|---|---|
|
Indication: Central Precocious Puberty Age: girls less than 8 years old and boys less than 9 years old |
Dose: Subcutaneous Injection – 50 mcg/kg/day Frequency: once daily Note: May be titrated upward by 10 mcg/kg/day if downregulation not achieved; may be discontinued at appropriate age of onset of puberty (eg, 11 years in females and 12 years in males), at physician's discretion |
|
Indication: Central Precocious Puberty Age: less than 2 years old |
Dose: Subcutaneous Injection – Not established Note: Safety and efficacy not established |
Administration
- Give subcutaneously or IM
- Follow exact schedule
Side Effect
- Hot flashes (57%)
- Cardiovascular changes or ischemia (19%)
- Fatigue (18%)
- Pain (13%)
- Peripheral edema (12%)
- Asthenia (10%)
- Gynocomastia (7%)
- Headache (7%)
- Testicular atrophy (7%)
- Anorexia (6%)
- Anemia (5%)
- Bone pain (5%)
- Constipation (7%)
- Urinary frequency (6%)
- Dermatitis (5%)
- Dizziness (5%)
- Nausea and vomiting (5%)
- Gastroenteritis (3%)
- Myalgia (3%)
- UTI (3%)
- Dyspnea (2%)
- Convulsion
- Depression
- Neuropathy
- Decreased bone density
- Hematuria
- Obstruction of ureter or bladder
- Impotence
- Sweating
- Implant site reactions (pain
- bruising
- edema)
- Spinal cord compression (rare)
Drug Interaction
Drug Interaction
| Drug Name | Risk Factors |
|---|---|
|
No interactions listed
|
-
|
Disease Interaction
Disease Interaction
| Disease Name | Risk Factors |
|---|---|
|
Undiagnosed vaginal bleeding
|
May mask serious condition
|
Pregnancy
Pregnancy
Lactation
Special Use
Precaution
Overdose
Pharmacology
Storage
Details coming soon
Data Sources
Clinical & regulatory information on this page is compiled from the following government sources:
DISCLAIMER: This drug information content is provided for informational purposes only and is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Patients should always consult their physician with any questions regarding a medical condition and to obtain medical advice and treatment.