Medicine Overview
Adult Dose
| Clinical Information | Administration Information |
|---|---|
|
Indication: Myasthenia gravis Age: Adult |
Dose: Intramuscular or Subcutaneous injection – 0.5-2.5 mg Frequency: doses are given at intervals according to response Note: Up to a total daily dose of 5-20 mg. |
|
Indication: Paralytic ileus and postoperative urinary retention Age: Adult |
Dose: Subcutaneous or Intramuscular injection – 0.5-2.5 mg Frequency: as required |
Child Dose
| Clinical Information | Administration Information |
|---|---|
|
Indication: Myasthenia gravis Age: less than 12 years |
Dose: Parenteral – 0.2-0.5 mg Note: repeated at suitable intervals throughout the day |
|
Indication: Paralytic ileus and postoperative urinary retention Age: Child |
Dose: Subcutaneous or Intramuscular injection – 0.125-1 mg Note: by subcutaneous or intramuscular injection |
Renal Dose
| Clinical Information | Administration Information |
|---|---|
|
Condition: Renal impairment |
Dose: Dosage Form – Dose adjustment may be required Note: Renal impairment: Dose adjustment may be required. |
Administration
- For medical professional use only
- Monitor vital signs
Side Effect
- Allergic Allergic reactions and anaphylaxis
- Neurologic Dizziness
- convulsions
- loss of consciousness
- drowsiness
- headache
- dysarthria
- miosis and visual changes
- Cardiovascular Cardiac arrhythmias (including bradycardia
- tachycardia
- A-V block and nodal rhythm) and nonspecific EKG changes have been reported
- as well as cardiac arrest
- Increased oral, pharyngeal and bronchial secretions
- dyspnea
- respiratory depression
- respiratory arrest and bronchospasm have been reported following the use of the injectable form
- Nausea
- emesis
- flatulence
- and increased peristalsis and salivation
- Urinary frequency
- Muscle cramps and spasms
- arthralgia
- Diaphoresis
- flushing and weaknes
- Anaphylaxis
Drug Interaction
Drug Interaction
| Drug Name | Risk Factors |
|---|---|
|
Anticholinergics
|
May reduce effects
|
|
Cholinergic agonists
|
May increase effects
|
Disease Interaction
Disease Interaction
| Disease Name | Risk Factors |
|---|---|
|
Mechanical GI obstruction
|
Risk of perforation
|
Pregnancy
Pregnancy
Lactation
Special Use
Precaution
Overdose
Pharmacology
Storage
Store in a cool and dry place, protected from light.
Data Sources
Clinical & regulatory information on this page is compiled from the following government sources:
DISCLAIMER: This drug information content is provided for informational purposes only and is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Patients should always consult their physician with any questions regarding a medical condition and to obtain medical advice and treatment.