Medicine Overview
Adult Dose
| Clinical Information | Administration Information |
|---|---|
|
Age: Adult |
Dose: Intravenous injection – Up to 50 mL per kg of body weight Frequency: daily Note: Equivalent to 3 g hydroxyethyl starch and 7.7 mEq sodium per kg of body weight. This dose is equivalent to 3500 mL of hydroxyethyl starch in sodium chloride injection for a 70 kg patient. |
Child Dose
| Clinical Information | Administration Information |
|---|---|
|
Age: Newborns and infants less than 2 years |
Dose: Intravenous – Mean dose of 16 mL/kg Note: Dosage in children should be adapted to the individual patient colloid needs, taking into account the disease state, as well as the hemodynamic and hydration status; give initial 10-20 mL by slow intravenous infusion and monitor for anaphylactoid reaction |
|
Age: 2-12 years |
Dose: Intravenous – Mean dose of 36 mL/kg Note: Dosage in children should be adapted to the individual patient colloid needs, taking into account the disease state, as well as the hemodynamic and hydration status; give initial 10-20 mL by slow intravenous infusion and monitor for anaphylactoid reaction |
Administration
- Give as IV infusion only
- Monitor blood pressure during administration
Side Effect
- hypersensitivity
- mild influenza-like symptoms
- bradycardia
- tachycardia
- bronchospasm
- non-cardiac pulmonary edema
- Skin and subcutaneous tissue disorders (Common, More than 1 to Less than 10%, dose dependent) Prolonged administration of high dosages of hydroxyethyl starch may cause pruritus (itching) which is an undesirable effect observed with all hydroxyethyl starches
Drug Interaction
Drug Interaction
| Drug Name | Risk Factors |
|---|---|
|
No interactions listed
|
-
|
Disease Interaction
Disease Interaction
| Disease Name | Risk Factors |
|---|---|
|
Fluid overload
|
Risk of pulmonary edema
|
|
Severe heart failure
|
May worsen heart condition
|
Pregnancy
Pregnancy
Lactation
Special Use
Precaution
Overdose
Pharmacology
Storage
Keep this medicine out of the sight and reach of children. Do not freeze. Do not store above 25°C.
Data Sources
Clinical & regulatory information on this page is compiled from the following government sources:
DISCLAIMER: This drug information content is provided for informational purposes only and is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Patients should always consult their physician with any questions regarding a medical condition and to obtain medical advice and treatment.