Medicine Overview
Adult Dose
| Clinical Information | Administration Information |
|---|---|
|
Indication: Polycystic ovarian syndrome; Female infertility Age: Adult Condition: Initial dose |
Dose: Injection (Subcutaneous or Intramuscular) – 150 IU Frequency: daily Duration: first 5 days Note: Adjust subsequent dosing based on clinical monitoring (serum oestradiol levels and vaginal ultrasound); dose adjustments should not be made more frequently than once every 2 days and should be 75-150 units per adjustment; maximum dose: 450 units daily; maximum course of treatment: 12 days; stop treatment when adequate response is obtained. |
|
Indication: Polycystic ovarian syndrome; Female infertility Age: Adult Condition: To induce ovulation |
Dose: Injection – 5000 to 10,000 units of chorionic gonadotrophin Frequency: single dose Note: Given 1-2 days after urofollitropin treatment is completed; urofollitropin treatment may be tried again in future cycles. |
Child Dose
| Clinical Information | Administration Information |
|---|---|
|
Age: Pediatric |
Dose: Safety and efficacy not established Note: Safety and efficacy not established |
Administration
- Give as subcutaneous injection
- Rotate injection sites
Side Effect
- Headache (11.1%)
- OHSS (11.1%, severe pelvic pain, N/V, weight gain)
- Nausea
- vomiting
- joint pain
- ovarian hyperstimulation syndrome
- adnexal torsion
- mild to moderate ovarian enlargement
- abdominal pain
- ovarian cysts
- local reaction at Injection site
- headaches
- haemoperitoneum
- benign and malignant ovarian neoplasms
- ascites
- pleural effusion
- hypovolaemia
- thromboembolic disorders
- Weight gain
- acne and gynaecomastia in men
- Ovarian cysts rupture
- intraperitoneal haemorrhage
Drug Interaction
Drug Interaction
| Drug Name | Risk Factors |
|---|---|
|
Drugs with luteinising hormone activity
|
Increased risk of ovarian hyperstimulation syndrome
|
Disease Interaction
Disease Interaction
| Disease Name | Risk Factors |
|---|---|
|
Ovarian cysts not from PCOS
|
Risk of cyst complications
|
|
Primary ovarian failure
|
Treatment ineffective
|
Pregnancy
Pregnancy
Lactation
Special Use
Precaution
Overdose
Pharmacology
Storage
Details coming soon
Data Sources
Clinical & regulatory information on this page is compiled from the following government sources:
DISCLAIMER: This drug information content is provided for informational purposes only and is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Patients should always consult their physician with any questions regarding a medical condition and to obtain medical advice and treatment.