Medicine Overview
Adult Dose
| Clinical Information | Administration Information |
|---|---|
|
Indication: Active immunisation against typhoid fever caused by Salmonella typhi Age: Adult |
Dose: Intramuscular Injection – 0.5 ml Frequency: Single dose Note: Recommended for both adults. Subjects who remain at risk of typhoid fever should be given a single booster dose of the vaccine with an interval of not more than 3 years. |
Child Dose
| Clinical Information | Administration Information |
|---|---|
|
Indication: Typhoid Fever Prophylaxis Age: Children 2 years of age or older |
Dose: Vaccine – 0.5 ml Frequency: single dose Note: Indicated for selective immunization against typhoid fever for people traveling to endemic areas |
|
Indication: Typhoid Fever Prophylaxis Condition: Subjects who remain at risk of typhoid fever |
Dose: Vaccine – single booster dose Note: Booster dose should be given with an interval of not more than 3 years |
Administration
- Give IM in deltoid muscle
- Children: inject in vastus lateralis
Side Effect
- Fever (2-32%)
- Malaise (4-24%)
- Headache (16-20%)
- Soreness (16%)
- Induration (5-15%)
- General aches (1-13%)
- Abdominal pain (6.4%)
- Nausea (Less than 8%)
- Diarrhea (2.9%)
- Vomiting (1.5%)
- Skin rash (1%)
- Pruritus (Less than 8%)
- Myalgia (3-7%)
- Cervical pain
- Diarrhea
- Flu-like syndrome
- Arthralgia
- Abdominal pain
- Loss of consciousness
- Perforated jejunum
- Weakness
Drug Interaction
Drug Interaction
| Drug Name | Risk Factors |
|---|---|
|
Antibiotics, Immunoglobulins (Various specific types)
|
May reduce the efficacy of typhoid vaccine
|
|
Mefloquine
|
May increase the efficacy of typhoid vaccine
|
Disease Interaction
Disease Interaction
| Disease Name | Risk Factors |
|---|---|
|
Hypersensitivity to components
|
Risk of allergic reaction
|
|
Immunodeficiency
|
Reduced vaccine effectiveness
|
Pregnancy
Pregnancy
Lactation
Special Use
Precaution
Overdose
Pharmacology
Storage
Keep out of the reach of children. Store at +2°C to +8°C. Transportation should also be at +2°C to +8°C. Do not freeze. Discard vaccine if frozen. Protect from light.
Data Sources
Clinical & regulatory information on this page is compiled from the following government sources:
DISCLAIMER: This drug information content is provided for informational purposes only and is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Patients should always consult their physician with any questions regarding a medical condition and to obtain medical advice and treatment.