Medicine Overview
Adult Dose
| Clinical Information | Administration Information |
|---|---|
|
Indication: Deep Vein Thrombosis/Acute Pulmonary Embolism Treatment |
Dose: Subcutaneous injection – 5 mg Frequency: once daily Duration: for 5-9 days; up to 26 days administered in clinical trials |
|
Indication: Deep Vein Thrombosis/Acute Pulmonary Embolism Treatment |
Dose: Subcutaneous injection – 7.5 mg Frequency: once daily Duration: for 5-9 days; up to 26 days administered in clinical trials |
Child Dose
| Clinical Information | Administration Information |
|---|---|
|
Age: Child |
Dose: Not specified – Safety and efficacy not established Note: Safety and efficacy not established |
Renal Dose
| Clinical Information | Administration Information |
|---|---|
|
Condition: Renal impairment (Creatinine Clearance less than 20 milliliters per minute) |
Dose: Contraindicated Note: Contraindicated |
|
Condition: Renal impairment (Creatinine Clearance 20-50 milliliters per minute) |
Dose: 1.5 mg Frequency: once daily |
Administration
- Give SC injection 6-8 hours after surgery
- Inject in abdomen area
Side Effect
- Anemia (1-20%)
- Fever (4-14%)
- Nausea (3-11%)
- Rash (7.5%)
- Dizziness (4%)
- Confusion (3%)
- Constipation (5-9%)
- Diarrhea (2-3%)
- Edema (9%)
- Headache (2-5%)
- Hypokalemia (1-4%)
- Hypotension (4%)
- Insomnia (4-5%)
- Purpura (4%)
- Thrombocytopenia (3%)
- Urinary retention (3%)
- Urinary Tract Infection (UTI) (2-4%)
- Vomiting (1-6%)
Drug Interaction
Drug Interaction
| Drug Name | Risk Factors |
|---|---|
|
Desirudin, Fibrinolytic Drugs (Streptokinase, Alteplase), Glycoprotein IIb/IIIa-receptor antagonists, Heparin, Heparinoids, LMWH
|
Increased risk of bleeding
|
Disease Interaction
Disease Interaction
| Disease Name | Risk Factors |
|---|---|
|
Active Bleeding
|
Risk of severe hemorrhage
|
|
Bacterial Endocarditis
|
Risk of complications
|
Pregnancy
Pregnancy
Lactation
Special Use
Precaution
Overdose
Pharmacology
Storage
Store below 25° C. Do not freeze.
Data Sources
Clinical & regulatory information on this page is compiled from the following government sources:
DISCLAIMER: This drug information content is provided for informational purposes only and is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Patients should always consult their physician with any questions regarding a medical condition and to obtain medical advice and treatment.