Medicine Overview
Adult Dose
| Clinical Information | Administration Information |
|---|---|
|
Indication: Total Parenteral nutrition Age: Adult Condition: First day of administration |
Dose: Intravenous – Initial infusion rate is 1 ml/min for the first 15 to 30 minutes, then can be increased to 2 ml/min if no adverse reactions occur. Infuse only 500 ml on the first day. Frequency: once daily Note: Administer intravenously via a peripheral vein or by central venous catheter. Fat emulsion should comprise no more than 60% of the patient's total caloric intake, with carbohydrates and amino acids comprising the remaining 40% or more of caloric intake. Do not exceed a daily dosage of 2.5 g/kg. |
|
Indication: Total Parenteral nutrition Age: Adult Condition: Subsequent days of administration |
Dose: Intravenous – Increase the dose from the first day Frequency: once daily Note: Administer intravenously via a peripheral vein or by central venous catheter. Fat emulsion should comprise no more than 60% of the patient's total caloric intake, with carbohydrates and amino acids comprising the remaining 40% or more of caloric intake. Do not exceed a daily dosage of 2.5 g/kg. Initial infusion rate rules from the first day may apply if restarting or adjusting. |
Child Dose
| Clinical Information | Administration Information |
|---|---|
|
Indication: Total Parenteral nutrition |
Dose: Intravenous – Fat emulsion should comprise no more than 60% of the patient's total caloric intake, with carbohydrates and amino acids comprising the remaining 40% or more of caloric intake Note: Administer intravenous via a peripheral vein or by central venous catheter |
|
Indication: Total Parenteral nutrition Age: Children |
Dose: Intravenous – Initial infusion rate is 0.1 ml/minute for the first 10 to 15 minutes Note: If no adverse reactions occur, the infusion rate can be increased to 1 g/kg in 4 hours. Do not exceed a daily dosage of 3 g/kg. |
Administration
- Take as directed
- Follow preparation instructions
Side Effect
- This may cause a rise in body temperature (incidence Less than 3%)
- less frequently shivering, chills and nausea/vomiting (incidenceLess than 1%)
- Reports of other adverse events in conjunction with 10% fat emulsion infusion are extremely rare
- less than one report of certain events per one million infusions
- Hypersensitivity reactions (anaphylactic reaction, skin rash, urticaria)
- respiratory symptoms (tachypnoea) and circulatory effects (hypertension, hypotension) have been described
- Thrombosis
- haemolysis
- reticulocytosis
- abdominal pain
- tiredness
- headaches
- flushing
- dyspnoea
- slight pressure over the eyes and dizziness have been reported
Drug Interaction
Drug Interaction
| Drug Name | Risk Factors |
|---|---|
|
No interactions listed
|
-
|
Disease Interaction
Disease Interaction
| Disease Name | Risk Factors |
|---|---|
|
Severe Fat Metabolism Disorder
|
Risk of metabolic complications
|
|
Severe Liver Damage
|
Risk of metabolic complications
|
Pregnancy
Pregnancy
Lactation
Special Use
Precaution
Overdose
Pharmacology
Storage
Store at room temperature (not exceeding 25° C). Protect from freezing and light. Emulsion which has been frozen should be discarded. Any remaining emulsion from an opened bag must be discarded. Do not use if the emulsion is discolored. This contains no preservatives.
Data Sources
Clinical & regulatory information on this page is compiled from the following government sources:
DISCLAIMER: This drug information content is provided for informational purposes only and is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Patients should always consult their physician with any questions regarding a medical condition and to obtain medical advice and treatment.