Medicine Overview
Adult Dose
| Clinical Information | Administration Information |
|---|---|
|
Age: Adult |
Dose: Initially 40 mg Frequency: once daily Note: May be increased to a maximum of 80 mg once daily as necessary. |
Child Dose
| Clinical Information | Administration Information |
|---|---|
|
Age: Pediatric |
Dose: Form – No approved pediatric dosage available Note: No approved pediatric dosage available |
Renal Dose
| Clinical Information | Administration Information |
|---|---|
|
Condition: Mild-to-severe renal impairment or end-stage renal disease |
Dose: Not specified Note: No dose adjustment is required. Patients with moderate-to-severe renal impairment are more likely to report high serum creatinine values. |
Administration
- Can take with or without food
- Take at same time daily
Side Effect
- Diarrhea (2%)
- Nausea
- Asthenia
- Fatigue
- Muscle spasm
- Dizziness
- Postural hypotension
- Cough
Drug Interaction
Drug Interaction
| Drug Name | Risk Factors |
|---|---|
|
Lithium
|
Reversibly increases serum concentration & toxicity
|
|
NSAIDs (Ibuprofen, Naproxen, Diclofenac, Celecoxib, Meloxicam, Indomethacin, Piroxicam, Ketorolac)
|
Attenuated antihypertensive effects & risk of worsening of renal function
|
Disease Interaction
Disease Interaction
| Disease Name | Risk Factors |
|---|---|
|
No specific contraindications listed
|
Monitor for general drug reactions
|
Pregnancy
Pregnancy
Lactation
Special Use
Precaution
Overdose
Pharmacology
Storage
keep in a dry place away from light and heat. Keep out of the reach of children.
Data Sources
Clinical & regulatory information on this page is compiled from the following government sources:
DISCLAIMER: This drug information content is provided for informational purposes only and is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Patients should always consult their physician with any questions regarding a medical condition and to obtain medical advice and treatment.