Medicine Overview

Indication

Know Medicine, Follow Guideline

Adult Dose

Clinical InformationAdministration Information
Indication: ICU Sedation
Age: Adult
Dose: Intravenous Loading Dose – 1 microgram/kilogram
Duration: over 10 minutes
Note: Titrate less frequently than every 30 minutes to prevent hypotension
Indication: ICU Sedation
Age: Adult
Dose: Intravenous Maintenance Infusion – 0.2-1.4 microgram/kilogram/hour
Note: Titrate less frequently than every 30 minutes to prevent hypotension

Child Dose

Clinical InformationAdministration Information
Age: Child
Dose: Safety and efficacy – not established
Note: Safety and efficacy not established

Renal Dose

Clinical InformationAdministration Information
Condition: Renal impairment (SL, BUC) all severities
Dose: Not specified
Note: No dosage adjustment necessary
Administration
  • For IV use only
  • Dilute in normal saline
Side Effect

Drug Interaction

Drug NameRisk Factors
Anaesthetics, sedatives, hypnotics, opiate agonists, other vasodilators, drugs with negative chronotropic effects (e.g. cardiac glycosides)
Enhanced pharmacologic effects

Disease Interaction

Disease NameRisk Factors
Heart Block (2nd/3rd degree)
Risk of cardiac complications
Uncontrolled Hypotension
Risk of dangerous blood pressure drop

Pregnancy

Lactation
Special Use
Precaution
Overdose
Pharmacology
Storage

Details coming soon

Data Sources

Clinical & regulatory information on this page is compiled from the following government sources:

DISCLAIMER: This drug information content is provided for informational purposes only and is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Patients should always consult their physician with any questions regarding a medical condition and to obtain medical advice and treatment.