Medicine Overview
Adult Dose
| Clinical Information | Administration Information |
|---|---|
|
Indication: Stage D2 metastatic carcinoma of the prostate Age: Adult |
Dose: Oral tablet – 50 mg Frequency: once daily (morning or evening) Note: Indicated for use in combination therapy with a luteinizing hormone-releasing hormone (LHRH) analog. |
Child Dose
| Clinical Information | Administration Information |
|---|---|
|
Age: Pediatric |
Dose: Not applicable – No approved pediatric dosage available Note: There is no approved pediatric dosage available for this medication. |
Renal Dose
| Clinical Information | Administration Information |
|---|---|
|
Condition: Renal Impairment |
Dose: Tablet – 50 mg Note: Renal impairment (as measured by creatinine clearance) had no significant effect on the elimination of total bicalutamide or the active R-enantiomer. No dosage adjustment is necessary. |
Administration
- Can be taken with or without food
- Take at the same time each day
Side Effect
- Hot flashes (53%)
- General pain (35%)
- Back pain (25%)
- Asthenia (22%)
- Constipation (22%)
- Pelvic pain (21%)
- Infection (18%)
- Nausea (15%)
- Dyspnea (13%)
- Edema (13%)
- Peripheral edema (13%)
- Diarrhea (12%)
- Hematuria (12%)
- Nocturia (12%)
- Abdominal pain (11%)
- Anemia (11%)
- Gynecomastia (9%)
- Rash (9%)
- UTI (9%)
- Chest pain (8%)
- Hypertension (8%)
- Vomiting (8%)
- Flu like symptoms (7%)
- Headache (7%)
- LFTs elevation (7%)
- Weight loss (7%)
- Anorexia (6%)
- Breast pain (6%)
- Anxiety (5%) Arthritis (5%)
Drug Interaction
Drug Interaction
| Drug Name | Risk Factors |
|---|---|
|
Coumarin Anticoagulants (Warfarin, Heparin, Dabigatran, Rivaroxaban, Apixaban, Edoxaban)
|
Enhances effect
|
Disease Interaction
Disease Interaction
| Disease Name | Risk Factors |
|---|---|
|
No specific contraindications listed
|
Monitor for general drug reactions
|
Pregnancy
Pregnancy
Lactation
Special Use
Precaution
Overdose
Pharmacology
Storage
Store at controlled room temperature, 20° to 25° C.
Data Sources
Clinical & regulatory information on this page is compiled from the following government sources:
DISCLAIMER: This drug information content is provided for informational purposes only and is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Patients should always consult their physician with any questions regarding a medical condition and to obtain medical advice and treatment.