Medicine Overview

Indication

Know Medicine, Follow Guideline

Adult Dose

Clinical InformationAdministration Information
Indication: Osteoarthritis
Age: Adult
Dose: Oral – 1 g
Frequency: once daily initially
Note: maintenance: 1-2 g/day by mouth in single daily dose or divided every 12 hours; not to exceed 2 g/day
Indication: Rheumatoid Arthritis
Age: Adult
Dose: Oral – 1 g
Frequency: once daily initially
Note: maintenance: 1-2 g/day by mouth in single daily dose or divided every 12 hours; not to exceed 2 g/day

Child Dose

Clinical InformationAdministration Information
Age: Child
Dose: Dose:
Note: Not recommended

Renal Dose

Clinical InformationAdministration Information
Condition: Creatinine Clearance 30-49 ml/min
Dose: Dosage Recommendation – 750 mg
Frequency: once daily
Note: Maximum initial dose: 750 mg once daily. Increase if needed to a maximum dose of 1.5 g daily.
Condition: Creatinine Clearance less than 30 ml/min
Dose: Dosage Recommendation – 500 mg
Frequency: once daily
Note: Maximum initial dose: 500 mg once daily. Increase if needed to a maximum dose of 1 g daily.
Administration
  • Should be taken with food
  • Take at regular intervals
Side Effect

Drug Interaction

Drug NameRisk Factors
Hypotensive agents
Antihypertensive effects may be reduced
Ciclosporin
May increase levels

Disease Interaction

Disease NameRisk Factors
Aspirin Allergy
Risk of severe allergic reaction
Severe Renal Impairment
Risk of kidney complications

Pregnancy

Lactation
Special Use
Precaution
Overdose
Pharmacology
Storage
Store at 25°C; excursions permitted to 15-30°C in well-closed container; dispense in light-resistant container.

Data Sources

Clinical & regulatory information on this page is compiled from the following government sources:

DISCLAIMER: This drug information content is provided for informational purposes only and is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Patients should always consult their physician with any questions regarding a medical condition and to obtain medical advice and treatment.