Medicine Overview
Adult Dose
| Clinical Information | Administration Information |
|---|---|
|
Indication: Acute myocardial infarction Age: Adult |
Dose: Intravenous – 30 mg Frequency: once Note: Administer as a single intravenous bolus over 5 to 10 seconds as soon as possible (within 30 minutes) after the onset of symptoms. Maximum: 50 mg. |
|
Indication: Acute myocardial infarction Age: Adult |
Dose: Intravenous – 35 mg Frequency: once Note: Administer as a single intravenous bolus over 5 to 10 seconds as soon as possible (within 30 minutes) after the onset of symptoms. Maximum: 50 mg. |
Child Dose
| Clinical Information | Administration Information |
|---|---|
|
Age: Child |
Dose: No approved pediatric dosage available Note: Not recommended |
Administration
- Given as IV injection
- Must be mixed properly before use
Side Effect
- Minor bleeding (22%)
- Reperfusion arrhythmias
- MI
- Fever
- Nausea
- Vomiting
- Cholesterol embolization
- Allergic reaction
Drug Interaction
Drug Interaction
| Drug Name | Risk Factors |
|---|---|
|
Heparin, oral Anticoagulants (Warfarin, Heparin, Dabigatran, Rivaroxaban, Apixaban, Edoxaban), antiplatelet drugs, other drugs that can affect platelet function
|
Increased risk of haemorrhage
|
Disease Interaction
Disease Interaction
| Disease Name | Risk Factors |
|---|---|
|
Severe Hypertension
|
Risk of cerebral bleeding
|
|
Recent Stroke History
|
Risk of cerebral hemorrhage
|
Pregnancy
Pregnancy
Lactation
Special Use
Precaution
Overdose
Pharmacology
Storage
Store lyophilized Tenecteplase at controlled room temperature not to exceed 30°C or under refrigeration 2-8°C. Do not use beyond the expiration date stamped on the vial.
Data Sources
Clinical & regulatory information on this page is compiled from the following government sources:
DISCLAIMER: This drug information content is provided for informational purposes only and is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Patients should always consult their physician with any questions regarding a medical condition and to obtain medical advice and treatment.