Medicine Overview
Adult Dose
| Clinical Information | Administration Information |
|---|---|
|
Indication: Kidney transplant patients Age: Adult Condition: As Mycophenolic Acid (MPA) (As Mycophenolate sodium) |
Dose: Oral – 720 mg Frequency: twice daily |
Child Dose
| Clinical Information | Administration Information |
|---|---|
|
Indication: Kidney transplant patients Age: 5 years or above Condition: As Mycophenolic Acid (MPA) (As Mycophenolate sodium) |
Dose: Oral – 400 mg/m2 Frequency: twice daily |
Renal Dose
| Clinical Information | Administration Information |
|---|---|
|
Age: Adult Condition: Renal impairment |
Dose: No dosage adjustment needed Note: No dosage adjustment needed in renal transplant patients experiencing delayed graft function post-operatively |
Administration
- Take on empty stomach
- Take 1 hour before or 2 hours after meals
Side Effect
- Hyperglycemia (44%)
- Hypercholesterolemia (41%)
- Hypomagnesemia (39%)
- Dyspnea (37%)
- Back pain (35%)
- Increased blood urea nitrogen (BUN) (35%)
- Leukopenia (34%)
- Pleural effusion (34%)
- Urinary Tract Infection (UTI) (34%)
- Increasing frequency of cough (31%)
- Hypocalcemia (30%)
- Hypertension (28%)
- Abdominal pain (27%)
- Peripheral edema (27%)
- Anemia (26%)
- Fever (23%)
- Nausea (23%)
- Hyperkalemia (22%)
- Diarrhea (21%)
- Infection (21%)
- Headache (16%)
- Melanoma (1.6-4.2%)
- Other malignancies (0.7-2.1%)
- Lymphoma (0.4-1%)
- Opportunistic infection (including herpes)
- Neutropenia
- GI bleeding
- Pulmonary fibrosis
- Progressive multifocal leukoencephalopathy
- Angioedema
- anaphylaxis
- fatal pulmonary fibrosis
Drug Interaction
Drug Interaction
| Drug Name | Risk Factors |
|---|---|
|
Live vaccines
|
May reduce efficacy
|
|
Aciclovir, valaciclovir, ganciclovir, valganciclovir
|
Increased plasma levels of both drugs
|
Disease Interaction
Disease Interaction
| Disease Name | Risk Factors |
|---|---|
|
Active severe infections
|
Can worsen infections due to immunosuppression
|
Pregnancy
Pregnancy
Lactation
Special Use
Precaution
Overdose
Pharmacology
Storage
Store at 25° C and Keep out of reach of children.
Data Sources
Clinical & regulatory information on this page is compiled from the following government sources:
DISCLAIMER: This drug information content is provided for informational purposes only and is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Patients should always consult their physician with any questions regarding a medical condition and to obtain medical advice and treatment.