Medicine Overview

Indication

Know Medicine, Follow Guideline

Adult Dose

Clinical InformationAdministration Information
Indication: Contraception
Age: Adult
Dose: Tablet – 1 active tablet
Frequency: once daily
Duration: 24 days, then 1 inert tablet (levomefolate calcium) once daily for 4 days
Indication: Premenstrual Dysphoric Disorder (PMDD)
Age: Adult
Condition: Symptoms of Premenstrual Dysphoric Disorder, but only if oral contraceptive is chosen as method of birth control
Dose: Tablet – 1 active tablet
Frequency: once daily
Duration: 24 days, then 1 inert tablet (levomefolate calcium) once daily for 4 days

Child Dose

Clinical InformationAdministration Information
Indication: Contraception
Age: 14 years and older (post-menarchal)
Dose: Tablet – 1 tablet (consisting of 3 mg drospirenone, 0.02 mg or 0.03 mg ethinyl estradiol, and 0.451 mg levomefolate calcium for 21-24 days, followed by 4-7 days of levomefolate calcium only)
Frequency: once daily
Note: by mouth (oral)
Indication: Moderate acne vulgaris
Age: 14 years and older (post-menarchal)
Dose: Tablet – 1 tablet (consisting of 3 mg drospirenone, 0.02 mg or 0.03 mg ethinyl estradiol, and 0.451 mg levomefolate calcium for 21-24 days, followed by 4-7 days of levomefolate calcium only)
Frequency: once daily
Note: by mouth (oral)

Renal Dose

Clinical InformationAdministration Information
Condition: Renal impairment
Dose: Tablet – Fixed dose
Note: Renal impairment: Contraindicated
Administration
  • Take one orange tablet daily for 21 days
  • Then take one light orange tablet daily for 7 days
Side Effect

Drug Interaction

Drug NameRisk Factors
CYP3A4 inducers
May decrease effectiveness of COCs or increase breakthrough bleeding

Disease Interaction

Disease NameRisk Factors
Renal impairment
Can cause fluid retention and electrolyte imbalance
Arterial/venous thrombosis risk
Can increase risk of blood clots

Pregnancy

Lactation
Special Use
Precaution
Overdose
Pharmacology
Storage
Keep below 30°C temperature, away from light & moisture. Keep out of the reach of children.

Data Sources

Clinical & regulatory information on this page is compiled from the following government sources:

DISCLAIMER: This drug information content is provided for informational purposes only and is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Patients should always consult their physician with any questions regarding a medical condition and to obtain medical advice and treatment.