Medicine Overview
Adult Dose
| Clinical Information | Administration Information |
|---|---|
|
Indication: Hyperkalaemia Age: Adult Condition: Oral |
Dose: Suspension in water or syrup or as sweetened paste – 15 g Frequency: up to 4 times daily Note: Not to be taken with fruit juices that have high potassium content. |
|
Indication: Hyperkalaemia Age: Adult Condition: Rectal |
Dose: Enema (suspension) – 30 g in 100 ml of 2% methylcellulose '450' and 100 ml of water Duration: retained for at least 9 hours, if possible Note: Higher doses may be retained for a shorter period of time. Irrigate colon after retention to remove the resin. |
Child Dose
| Clinical Information | Administration Information |
|---|---|
|
Indication: Acute hyperkalaemia Age: Child |
Dose: Oral – 1 g/kg Frequency: daily in divided doses |
|
Indication: Maintenance hyperkalaemia Age: Child |
Dose: Oral – 500 mg/kg Frequency: daily |
Administration
- For oral use: Mix with water or syrup
- For rectal use: Mix with appropriate solution
Side Effect
- GI disturbance
- Constipation
- Hypokalemia
- Hypocalcemia
- Hypomagnesemia
- Sodium retention
- Nausea
- Vomiting
- GI tract ulceration or necrosis, which could lead to perforation
- Fecal impaction after rectal administration (especially in children)
- Acute bronchitis or bronchopneumonia associated with inhalation of polystyrene particles (rare)
Drug Interaction
Drug Interaction
| Drug Name | Risk Factors |
|---|---|
|
Thyroxine, lithium salts
|
Reduces absorption
|
|
Cardiac glycosides
|
Enhances adverse effects
|
Disease Interaction
Disease Interaction
| Disease Name | Risk Factors |
|---|---|
|
Bowel obstruction
|
Risk of bowel perforation
|
|
Hypokalemia
|
Can worsen low potassium levels
|
Pregnancy
Pregnancy
Lactation
Special Use
Precaution
Overdose
Pharmacology
Storage
Store below 30°C. Keep out of the reach of children. Suspension of this drug should be freshly prepared and not to be stored beyond 24 hours.
Data Sources
Clinical & regulatory information on this page is compiled from the following government sources:
DISCLAIMER: This drug information content is provided for informational purposes only and is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Patients should always consult their physician with any questions regarding a medical condition and to obtain medical advice and treatment.