Medicine Overview

Indication

Know Medicine, Follow Guideline

Adult Dose

Clinical InformationAdministration Information
Indication: Diarrhea-predominant irritable bowel syndrome (IBS-D)
Age: Adult
Dose: Tablet – 100 mg
Frequency: twice daily
Note: Take with food; discontinue in patients who develop severe constipation lasting greater than 4 days
Indication: Diarrhea-predominant irritable bowel syndrome (IBS-D)
Age: Adult
Condition: Mild-to-moderate hepatic impairment (Child-Pugh A or B)
Dose: Tablet – 75 mg
Frequency: twice daily
Note: Monitor for impaired mental or physical abilities needed to perform potentially hazardous activities

Child Dose

Clinical InformationAdministration Information
Age: Pediatric
Dose: Dosage – Not available
Note: No approved pediatric dosage available
Administration
  • Take with food
  • Take at regular intervals
Side Effect

Drug Interaction

Drug NameRisk Factors
No interactions listed
-

Disease Interaction

Disease NameRisk Factors
No gallbladder
Risk of sphincter of Oddi spasm
Gallbladder/biliary duct obstruction
Can worsen biliary complications

Pregnancy

Lactation
Special Use
Precaution
Overdose
Pharmacology
Storage
Store in a cool & dry place, protect from light. Keep out of the reach of children.

Data Sources

Clinical & regulatory information on this page is compiled from the following government sources:

DISCLAIMER: This drug information content is provided for informational purposes only and is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Patients should always consult their physician with any questions regarding a medical condition and to obtain medical advice and treatment.