Medicine Overview
Adult Dose
| Clinical Information | Administration Information |
|---|---|
|
Indication: Symptomatic relief of tension, anxiety and agitation Age: Adult |
Dose: Oral – 6 to 18 mg Frequency: in equally divided doses Note: Recommended initial adult daily dosage depending on the severity of symptoms and response of the patient; treatment should be initiated by lower doses and adjusted as necessary; maximum recommended dose is 60 mg daily; overall treatment should not be more than 2 – 4 weeks, followed by a tapering-off process of up to 6 – 8 weeks |
|
Indication: Symptomatic relief of tension, anxiety and agitation Age: Adult |
Dose: Oral – 6 to 30 mg Frequency: in divided doses Note: Optimal dosage range in individual patients; maximum recommended dose is 60 mg daily; overall treatment should not be more than 2 – 4 weeks, followed by a tapering-off process of up to 6 – 8 weeks |
Child Dose
| Clinical Information | Administration Information |
|---|---|
|
Age: Child |
Dose: Not recommended Note: Bromazepam is not recommended in children as there is insufficient evidence of safety and efficacy in this group. |
Renal Dose
| Clinical Information | Administration Information |
|---|---|
|
Condition: Renal impairment |
Dose: No formal pharmacokinetic study has been conducted and no population pharmacokinetic data was collected in patients with renal impairment Note: No dosage adjustment needed. |
Administration
- Can be taken with or without food
- Take at regular intervals as prescribed
Side Effect
- Drowsiness
- sedation
- muscle weakness and ataxia
- less frequently vertigo
- headache
- confusion
- depression
- slurred speech
- changes in libido
- tremor
- visual disturbances
- urinary retention
- GI disturbances
- changes in salivation and amnesia
- jaundice
- blood disorders and hypersensitivity reactions
- pain and thrombophlebitis
- raised liver enzyme values
- paradoxical excitation
Drug Interaction
Drug Interaction
| Drug Name | Risk Factors |
|---|---|
|
CYP450 inhibitors
|
May enhance activity
|
|
Disulfiram, Cimetidine
|
Elevated plasma levels
|
Disease Interaction
Disease Interaction
| Disease Name | Risk Factors |
|---|---|
|
CNS Depression, Coma
|
Can worsen consciousness level
|
|
Respiratory Depression, Sleep Apnea
|
Can worsen breathing
|
Pregnancy
Pregnancy
Lactation
Special Use
Precaution
Overdose
Pharmacology
Storage
Keep in a dry place away from light and heat. Keep out of the reach of children.
Data Sources
Clinical & regulatory information on this page is compiled from the following government sources:
DISCLAIMER: This drug information content is provided for informational purposes only and is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Patients should always consult their physician with any questions regarding a medical condition and to obtain medical advice and treatment.