Question 1

What is this medicine for, and how does it work?

Accepted Answer

This is a neurological disorder medication. It's used to treat chorea associated with Huntington's disease. It works by restoring the balance of certain chemicals in the brain to reduce involuntary movements.

Question 2

When and how should this medicine be taken?

Accepted Answer

• Take with food • Take at same time each day • Swallow tablet whole • Do not chew or crush

Question 3

When should this medicine not be used?

Accepted Answer

• Depression • Drowsiness • Parkinson's • Heart rhythm issues

Question 4

What precautions should be taken before using this medicine?

Accepted Answer

• Can cause depression and suicidal thoughts, monitor mood changes • May cause drowsiness, avoid driving if affected • Can worsen Parkinson's disease symptoms • May cause irregular heartbeat, use caution in patients with heart conditions

Question 5

Is it safe to use this medicine during pregnancy?

Accepted Answer

• Limited human data available • Animal studies show potential for harm • Use only if clearly needed

Question 6

Can this medicine be used while breastfeeding?

Accepted Answer

• Can cause depression and suicidal thoughts, monitor mood changes • May cause drowsiness, avoid driving if affected • Can worsen Parkinson's disease symptoms • May cause irregular heartbeat, use caution in patients with heart conditions

Question 7

What should be done if a dose is missed?

Accepted Answer

• If you miss a dose, take it as soon as you remember. • However, if it's almost time for your next dose, skip the missed dose. • Never take two doses together. • For once-daily dosing: If you remember on the same day, take the dose. • For twice-daily dosing: If more than 6 hours until your next dose, take the missed dose. • Take your next dose at the regular time. • If you're unsure, contact your doctor or pharmacist.

Question 8

What should be done in case of an overdose?

Accepted Answer

• Symptoms: Sedation, depression, parkinsonism. • Treatment: Neurologic monitoring, supportive care.

Question 9

What should be done if side effects are experienced?

Accepted Answer

• Common side effects: Sleepiness, diarrhea, dry mouth, fatigue • What to do: Avoid driving; Stay hydrated; Report severe drowsiness; Take as prescribed; Stop taking the medication and seek medical advice if any severe side effect or unusual symptoms occur.

Question 10

What medical indications are treated with Deutetrabenazine?

Accepted Answer

Deutetrabenazine (Atypical Neuroleptic Drugs) is a pharmaceutical active substance. It is indicated for the treatment of Chorea associated with Huntington Disease, Tardive Dyskinesia.

Question 11

What is the recommended dosage for Deutetrabenazine?

Accepted Answer

Standard adult dosage: Oral – 6 mg (once daily). Pediatric dosage: Not applicable – No approved dosage. Always consult a registered physician for individualized dosage adjustments based on clinical assessment.

Question 12

Is Deutetrabenazine safe during pregnancy and breastfeeding?

Accepted Answer

Deutetrabenazine is classified under Pregnancy Category "Not Assigned". Always consult your healthcare provider or OB/GYN before taking this medication during pregnancy or lactation.

Question 13

What are the common side effects of Deutetrabenazine?

Accepted Answer

**More than 10%**; Somnolence (11%); **1-10%**; Diarrhea (9%);Dry mouth (9%);Fatigue (9%);Urinary Tract Infection (UTI) (7%);Insomnia (7%);Anxiety (4%);Constipation (4%);Contusion (4%);Dizziness (4%);Akathisia, agitation

Clinical Information	Administration Information
Indication: Chorea associated with Huntington disease	Dose: Oral – 6 mg Frequency: once daily Note: Initial dose when not being switched from tetrabenazine. Dose is determined individually for each patient based on reduction of chorea and tolerability. May increased dose at weekly intervals in increments of 6 mg/day; not to exceed 48 mg/day. Administer doses greater than 12 mg/day in 2 divided doses.
Indication: Tardive Dyskinesia	Dose: Oral – 6 mg Frequency: twice daily Note: Initial dose when not being switched from tetrabenazine. Dose is determined individually for each patient based on reduction of tardive dyskinesia and tolerability. May increased dose at weekly intervals in increments of 6 mg/day; not to exceed 48 mg/day.

Drug Name	Risk Factors
Dopamine antagonists, Antipsychotics (Haloperidol, Risperidone, Quetiapine, Olanzapine, Clozapine, Aripiprazole)	May increase risk for parkinsonism, NMS, and akathisia
Alcohol, sedating drugs	May worsen somnolence associated with deutetrabenazine

Disease Name	Risk Factors
Suicidal Patients with Huntington Disease	Risk of suicide attempt
Untreated/Inadequately Treated Depression	Risk of worsening depression

Medicine Overview

Indication

What is this medicine for, and how does it work?

When and how should this medicine be taken?

When should this medicine not be used?

What precautions should be taken before using this medicine?

Is it safe to use this medicine during pregnancy?

Can this medicine be used while breastfeeding?

What should be done if a dose is missed?

What should be done in case of an overdose?

What should be done if side effects are experienced?

Adult Dose

Child Dose

Drug Interaction

Disease Interaction

Pregnancy

Data Sources