Medicine Overview

Indication

Know Medicine, Follow Guideline

Adult Dose

Clinical InformationAdministration Information
Indication: Local Anesthesia
Condition: Local infiltration
Dose: Injection – 0.25%
Note: May increase up to 175 mg (70 mL)
Indication: Regional Anesthesia
Condition: Sympathetic block
Dose: Injection – 0.25%
Frequency: 50-125 mg (20-50 mL)

Child Dose

Clinical InformationAdministration Information
Indication: Local Anesthesia
Age: <12 years
Dose: Injection
Note: Not recommended.
Indication: Local Anesthesia
Age: infants <6 months
Condition: if necessary
Dose: Injection – decreased dose by 30%
Note: Not recommended.

Renal Dose

Clinical InformationAdministration Information
Condition: Renal impairment (All severities)
Dose: Use with caution
Note: Pharmacokinetics not evaluated; substantially excreted by the kidneys; may increase bupivacaine exposure and risk of systemic toxicities; consider frequent monitoring for adverse reactions
Administration
  • For medical professional use only
  • Must be administered by healthcare provider
Side Effect

Drug Interaction

Drug NameRisk Factors
Hyaluronidase (Enzyme preparations)
Enhanced adverse effects
Cimetidine, Ranitidine
Decreased clearance resulting in increased plasma concentrations

Disease Interaction

Disease NameRisk Factors
IV Regional Anaesthesia
Risk of systemic toxicity
Paracervical Block in Obstetrics
Risk to fetus

Pregnancy

Lactation
Special Use
Precaution
Overdose
Pharmacology
Storage
Keep in a cool & dry place, protected from light. Keep out of the reach of children.

Data Sources

Clinical & regulatory information on this page is compiled from the following government sources:

DISCLAIMER: This drug information content is provided for informational purposes only and is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Patients should always consult their physician with any questions regarding a medical condition and to obtain medical advice and treatment.