Question 1

What is this medicine for, and how does it work?

Accepted Answer

This is an opioid pain medication combined with an opioid antagonist. It's used to control moderate to severe pain. The pain-relieving component reduces pain, while the antagonist component helps prevent misuse of the drug.

Question 2

When and how should this medicine be taken?

Accepted Answer

• Can be given IM, IV or by infusion • For IV, dilute in 100-200 mL of fluid • Infuse over 30-60 minutes

Question 3

When should this medicine not be used?

Accepted Answer

• In severe hearing problems • In kidney failure • In myasthenia gravis • In newborns

Question 4

What precautions should be taken before using this medicine?

Accepted Answer

• Can cause hearing loss more often than similar drugs • Regular hearing tests recommended • Rarely causes balance problems • Can harm kidneys - regular kidney function tests needed • Use carefully in patients with existing kidney problems • Can cause nerve damage • Use cautiously in premature babies and newborns due to immature kidneys

Question 5

Is it safe to use this medicine during pregnancy?

Accepted Answer

• Limited data available for use in pregnancy • Use only if potential benefit justifies the potential risk to the fetus

Question 6

Can this medicine be used while breastfeeding?

Accepted Answer

• Can cause hearing loss more often than similar drugs • Regular hearing tests recommended • Rarely causes balance problems • Can harm kidneys - regular kidney function tests needed • Use carefully in patients with existing kidney problems • Can cause nerve damage • Use cautiously in premature babies and newborns due to immature kidneys

Question 7

What should be done if a dose is missed?

Accepted Answer

• If you miss a dose, take it as soon as you remember. • However, if it's almost time for your next dose, skip the missed dose. • Never take two doses together. • For once-daily dosing: If you remember the next day, just take that day's dose. • For twice-daily dosing: If more than 8 hours until your next dose, take the missed dose. • Take your next dose at the regular time. • If you're unsure, contact your doctor or pharmacist.

Question 8

What should be done in case of an overdose?

Accepted Answer

• Symptoms: Neurotoxicity, nephrotoxicity. • Treatment: Hemodialysis, auditory function monitoring.

Question 9

What should be done if side effects are experienced?

Accepted Answer

• Common side effects: Blood disorders, loss of appetite, diarrhea, breathing problems, kidney problems • What to do: Regular hearing/kidney tests; Report unusual symptoms; Monitor urine output; Complete full course; Stop taking the medication and seek medical advice if any severe side effect or unusual symptoms occur.

Question 10

What medical indications are treated with Kanamycin?

Accepted Answer

Kanamycin (Aminoglycosides) is a pharmaceutical active substance. It is indicated for the treatment of Susceptible Infections.

Question 11

What is the recommended dosage for Kanamycin?

Accepted Answer

Standard adult dosage: Intravenous Administration – 5-7.5 mg/kg/dose (divided every 8-12 hours). Pediatric dosage: Intramuscular or intravenous – 15 mg/kg/day (equally divided doses every 8 to 12 hours). Always consult a registered physician for individualized dosage adjustments based on clinical assessment.

Question 12

Is Kanamycin safe during pregnancy and breastfeeding?

Accepted Answer

Kanamycin is classified under Pregnancy Category "D". Always consult your healthcare provider or OB/GYN before taking this medication during pregnancy or lactation.

Question 13

What are the common side effects of Kanamycin?

Accepted Answer

**Frequency Not Defined**; Agranulocytosis;Anorexia;Diarrhea;Dyspnea;Edema;Elevated BUN;Enterocolitis;Headache;Incr salivation;Muscle cramps;Muscle weakness;Nausea;Nephrotoxicity;Neurotoxicity;Ototoxicity;Pruritus;Pseudo

Clinical Information	Administration Information
Indication: Susceptible Infections	Dose: Intravenous Administration – 5-7.5 mg/kg/dose Frequency: divided every 8-12 hours Note: not to exceed 15 mg/kg/day divided every 6-12 hours; administer slowly
Indication: Susceptible Infections	Dose: Intramuscular Administration – 5-7.5 mg/kg/dose Frequency: divided every 8-12 hours Note: not to exceed 15 mg/kg/day intramuscular divided every 12 hours at equally divided intervals; continuously high blood levels are desired; daily dose of 15 mg/kg may be given divided every 6-8 hours

Clinical Information	Administration Information
Indication: Bacterial infection	Dose: Intramuscular or intravenous – 15 mg/kg/day Frequency: equally divided doses every 8 to 12 hours Note: Max Dose: 1.5 g/day
Indication: Tuberculosis Age: Children	Dose: Intramuscular or intravenous – 15–30 mg/kg Frequency: once daily, 5–7 times per week Note: Max Dose: 1 g daily

Clinical Information	Administration Information
Condition: Renal Impairment Creatinine Clearance 50-80 mL/min	Dose: 60-90% of usual dose Note: Or give every 8-12 hours
Condition: Renal Impairment Creatinine Clearance 10-50 mL/min	Dose: 30-70% of usual dose Note: Or give every 12 hours

Medicine Overview

Indication

What is this medicine for, and how does it work?

When and how should this medicine be taken?

When should this medicine not be used?

What precautions should be taken before using this medicine?

Is it safe to use this medicine during pregnancy?

Can this medicine be used while breastfeeding?

What should be done if a dose is missed?

What should be done in case of an overdose?

What should be done if side effects are experienced?

Adult Dose

Child Dose

Renal Dose

Drug Interaction

Disease Interaction

Pregnancy

Data Sources