Medicine Overview
Adult Dose
| Clinical Information | Administration Information |
|---|---|
|
Indication: Hypocalcemia Condition: Mild (ionized calcium 1-1.2 mmol/L) |
Dose: Intravenous – 1-2 g Duration: over 2 hours Note: Management of non-life-threatening symptoms |
|
Indication: Hypocalcemia Condition: Severe (ionized calcium less than 1 mmol/L) without seizure or tetany |
Dose: Intravenous – 0.5 mg/kg/hour Note: May be increased to 2 mg/kg/hour; not to exceed 3-4 g intravenous over 4 hours |
Child Dose
| Clinical Information | Administration Information |
|---|---|
|
Indication: Hypocalcemia Age: Neonates Condition: Severe |
Dose: Intravenous – 200-800 mg/kg/day Frequency: continuous infusion or divided every 6 hours as intermittent infusions Note: Treatment of conditions arising from calcium deficiency (e.g., hypocalcemic tetany, hypoparathyroidism) |
|
Indication: Hypocalcemia Age: Infants/children Condition: Severe |
Dose: Intravenous – 200-500 mg/kg/day Frequency: continuous infusion or divided every 6 hours as intermittent infusions Note: Treatment of conditions arising from calcium deficiency (e.g., hypocalcemic tetany, hypoparathyroidism) |
Renal Dose
| Clinical Information | Administration Information |
|---|---|
|
Condition: Renal impairment |
Dose: Not mentioned – Initiate with the lower limit of the dosage range Note: Monitor serum calcium levels every 4 hours |
Administration
- Take with food
- Take with full glass of water
Side Effect
- Bradycardia
- Hypotension
- Headache
- Constipation
- Diarrhea
- Flatulence
- Nausea
- Vomiting
- Hypomagnesemia
- Hypophosphatemia
- Extravasation necrosis
- anorexia
- nausea
- vomiting
- constipation
- abdominal pain
- muscle weakness
- mental disturbances
- polydipsia
- polyuria
- nephrocalcinosis
- renal calculi
- chalky taste
- hot flushes and peripheral vasodilation
- Cardiac arrhythmias and coma
Drug Interaction
Drug Interaction
| Drug Name | Risk Factors |
|---|---|
|
Thiazide diuretics (Chlorothiazide, Chlorthalidone, Hydrochlorothiazide, Indapamide, Metolazone)
|
May result in milk-alkali syndrome and hypercalcaemia
|
|
Digoxin
|
May potentiate toxicity
|
Disease Interaction
Disease Interaction
| Disease Name | Risk Factors |
|---|---|
|
Calcium Renal Calculi, History of Renal Calculi
|
Risk of kidney stone formation
|
|
Hypercalcaemia, Hypercalciuria
|
Can worsen calcium levels
|
Pregnancy
Pregnancy
Lactation
Special Use
Precaution
Overdose
Pharmacology
Storage
Details coming soon
Data Sources
Clinical & regulatory information on this page is compiled from the following government sources:
DISCLAIMER: This drug information content is provided for informational purposes only and is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Patients should always consult their physician with any questions regarding a medical condition and to obtain medical advice and treatment.