Question 1

What is this medicine for, and how does it work?

Accepted Answer

This is an ACE inhibitor that treats high blood pressure and heart disease. It works by inhibiting angiotensin-converting enzyme, dilating blood vessels.

Question 2

When and how should this medicine be taken?

Accepted Answer

• Take on empty stomach • Take 1 hour before or 2 hours after meals • Take with water • Monitor blood pressure regularly

Question 3

When should this medicine not be used?

Accepted Answer

• In last 6 months of pregnancy
• In severe renal disease
• History of angioedema

Question 4

What precautions should be taken before using this medicine?

Accepted Answer

• Use carefully in patients with kidney problems • Monitor closely if used with certain other medications • Use with caution during pregnancy and breastfeeding

Question 5

Is it safe to use this medicine during pregnancy?

Accepted Answer

• Category C in first trimester • Category D in second and third trimesters • Stop as soon as pregnancy detected • Can cause serious harm to the baby in later stages of pregnancy

Question 6

Can this medicine be used while breastfeeding?

Accepted Answer

• Use carefully in patients with kidney problems • Monitor closely if used with certain other medications • Use with caution during pregnancy and breastfeeding

Question 7

What should be done if a dose is missed?

Accepted Answer

• Take missed dose ASAP. • Skip if near next dose. • Never double dose. • In case of twice daily dose: Take Take the missed dose, if more than 6 hours to next dose. • If unsure, consult doctor.

Question 8

What should be done in case of an overdose?

Accepted Answer

• Symptoms: Severe hypotension, bradycardia. • Treatment: Saline infusion, atropine. • Complications: Renal failure, shock.

Question 9

What should be done if side effects are experienced?

Accepted Answer

• Common side effects: High potassium, allergic reactions, skin rash, taste changes, low blood pressure, cough, chest pain • What to do: Regular blood pressure monitoring; Take on empty stomach; Report persistent cough; Check potassium levels; Monitor kidney function; Stop taking the medication and seek medical advice if any severe side effect or unusual symptoms occur.

Question 10

What medical indications are treated with Captopril?

Accepted Answer

Captopril (Angiotensin-Converting Enzyme (ACE) Inhibitor) is a pharmaceutical active substance. It is indicated for the treatment of Congestive Heart Failure, Diabetic Nephropathy, Hypertension (HTN), Post Myocardial Infarction (MI).

Question 11

What is the recommended dosage for Captopril?

Accepted Answer

Standard adult dosage: Tablet – 12.5–25 mg (twice daily). Pediatric dosage: Oral – 0.15 mg/kg (2 or 3 divided doses). Always consult a registered physician for individualized dosage adjustments based on clinical assessment.

Question 12

Is Captopril safe during pregnancy and breastfeeding?

Accepted Answer

Captopril is classified under Pregnancy Category "D". Always consult your healthcare provider or OB/GYN before taking this medication during pregnancy or lactation.

Question 13

What are the common side effects of Captopril?

Accepted Answer

**More than 10%**; Hyperkalemia (1-11%); **1-10%**; Hypersensitivity rxns (4-7%);Skin rash (4-7%);Dysgeusia (2-4%);Hypotension (1-2.5%);Pruritus (2%);Cough (0.5-2%);Chest pain (1%);Palpitations (1%);Proteinuria (1%);Tach

Clinical Information	Administration Information
Indication: Hypertension Age: Adult Condition: Initial dose	Dose: Tablet – 12.5–25 mg Frequency: twice daily Note: Increased if necessary up to 150 mg daily in 2 divided doses; doses to be increased at intervals of at least 2 weeks; once daily dosing may be appropriate if other concomitant antihypertensive drugs are taken.
Indication: Essential hypertension Age: Adult Condition: Initial dose for volume depletion, cardiac decompensation, or renovascular hypertension	Dose: Tablet – 6.25–12.5 mg Frequency: once daily for 1 dose, then twice daily Note: Increased if necessary up to 100 mg daily in 1–2 divided doses; doses to be increased at intervals of at least 2 weeks; once daily dosing may be appropriate if other concomitant antihypertensive drugs are taken.

Clinical Information	Administration Information
Indication: Hypertension Age: Neonates and infants	Dose: Oral – 0.15 mg/kg Frequency: 2 or 3 divided doses Note: Maximum: 6 mg/kg; adjusted according to response
Indication: Hypertension Age: Children and adolescents	Dose: Oral – 0.3 mg/kg Frequency: 2 or 3 divided doses Note: Maximum: 6 mg/kg; adjusted according to response

Clinical Information	Administration Information
Condition: Renal impairment: Creatinine Clearance less than 10 ml/min	Dose: 6.25 mg Frequency: once daily Note: Maximum: 37.5 mg/day
Condition: Renal impairment: Creatinine Clearance 10-20 ml/min	Dose: 12.5 mg Frequency: once daily Note: Maximum: 75 mg/day

Drug Name	Risk Factors
NSAIDs (Ibuprofen, Naproxen, Diclofenac, Celecoxib, Meloxicam, Indomethacin, Piroxicam, Ketorolac)	Reduces hypotensive action and increases nephrotoxicity risk
K supplements, Potassium-sparing diuretics (Amiloride, Eplerenone, Spironolactone, Triamterene), other K-increasing drugs	Additive hyperkalaemic effect

Disease Name	Risk Factors
Bilateral Renal Artery Stenosis	Can cause acute kidney failure
Hereditary Angioedema	Can trigger severe allergic reactions

Medicine Overview

Indication

What is this medicine for, and how does it work?

When and how should this medicine be taken?

When should this medicine not be used?

What precautions should be taken before using this medicine?

Is it safe to use this medicine during pregnancy?

Can this medicine be used while breastfeeding?

What should be done if a dose is missed?

What should be done in case of an overdose?

What should be done if side effects are experienced?

Adult Dose

Child Dose

Renal Dose

Drug Interaction

Disease Interaction

Pregnancy

Data Sources