Medicine Overview
Adult Dose
| Clinical Information | Administration Information |
|---|---|
|
Indication: Ovulation Induction Age: Women |
Dose: Subcutaneous Injection – 75 international units of rFSH Frequency: once daily Duration: at least the first 7 days Note: Dose is increased by 25 or 75 international units at weekly intervals until follicular growth and/or serum estradiol levels indicate an adequate response. Final oocyte maturation is achieved with 5000 to 10,000 international units of human chorionic gonadotropin when acceptable pre-ovulatory state is achieved. Intercourse should occur daily starting the day prior to human chorionic gonadotropin administration until ovulation. |
|
Indication: Assisted Reproductive Technology (ART) Age: Women |
Dose: Subcutaneous Injection – 150 to 300 international units of rFSH Duration: at least the first 4 days Note: Subsequent doses are adjusted based upon ovarian response. Final oocyte maturation is induced with 5000 to 10,000 international units of human chorionic gonadotropin. Oocyte retrieval is performed 34 to 36 hours later. |
Child Dose
| Clinical Information | Administration Information |
|---|---|
|
Age: Child Condition: No approved pediatric dosage available |
Dose: Not applicable – Not applicable Note: No approved pediatric dosage available |
Administration
- For subcutaneous injection only
- Rotate injection sites
Side Effect
- Recombinant FSH sometimes excites the ovaries too much
- This may cause pelvic pain or breathing problems
- It may also make you urinate less
- In rare cases, patients with this problem have had serious lung problems, including fluid in the lungs
- troublebreathing
- worsening of asthma blood clots
- Severe Pelvic pain
- Chest pain
- or Abdominal pain
- Nausea
- Vomiting
- Sudden weight gain
- Bloating
- Trouble
- Breathing
- Recombinant FSH may cause twins or multiple births
Drug Interaction
Drug Interaction
| Drug Name | Risk Factors |
|---|---|
|
No interactions listed
|
-
|
Disease Interaction
Disease Interaction
| Disease Name | Risk Factors |
|---|---|
|
Tumors Of The Ovary, Breast, Uterus
|
Risk of tumor growth stimulation
|
|
Undiagnosed Vaginal Bleeding
|
Risk of underlying serious condition
|
Pregnancy
Pregnancy
Lactation
Special Use
Precaution
Overdose
Pharmacology
Storage
Store at 2°C to 8°C (in a refrigerator). Do not keep in deep freeze. Can be stored below 25°C for a maximum of 3 months. Protect from light & keep in dry place .
Data Sources
Clinical & regulatory information on this page is compiled from the following government sources:
DISCLAIMER: This drug information content is provided for informational purposes only and is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Patients should always consult their physician with any questions regarding a medical condition and to obtain medical advice and treatment.