Medicine Overview
Adult Dose
| Clinical Information | Administration Information |
|---|---|
|
Indication: Acute treatment of migraine attack with or without aura Age: Adult |
Dose: Intranasal spray – 10 mg Frequency: once daily Note: The dose is administered as a single nasal spray in 1 nostril. If the migraine has not resolved by 2 hours after taking, or returns after a transient improvement, 1 additional dose may be administered at least 1 hour after the first dose. If headache returns, may repeat 10 mg single dose once after 1 hour; not to exceed 30 mg/day. |
|
Indication: Acute treatment of migraine attack with or without aura Age: Adult |
Dose: Intranasal spray – 20 mg Frequency: once daily Note: The dose is administered as a single nasal spray in 1 nostril. If the migraine has not resolved by 2 hours after taking, or returns after a transient improvement, 1 additional dose may be administered at least 2 hours after the first dose. If headache returns, may repeat 20 mg single dose once after 2 hours; not to exceed 40 mg/day. |
Child Dose
| Clinical Information | Administration Information |
|---|---|
|
Age: less than 18 years |
Dose: Not established Note: Safety and efficacy not established |
Administration
- Use one spray in one nostril
- Do not spray into both nostrils
Side Effect
- Bad/unusual taste (13.5-24.5%)
- Gastrointestinal nausea/vomiting (11-13.5%)
- Disorder/discomfort of nasal cavity/sinuses (2.5-3.8%)
- Throat discomfort (0.8-2.4%)
- Dizziness/vertigo (1-1.7%)
- Burning sensation (0.4-1.4%)
- Atypical Sensations Tingling
- numbness
- pressure sensation
- cold sensation
- feeling of tightness
- Cardiovascular Flushing
- hypertension
- palpations
- tachycardia
- arrhythmia
- edema
- Chest tightness/discomfort
- chest pressure/heaviness
- Disturbance of hearing
- ear infections
- Eye irritation and visual disturbances
- Gastrointestinal Abdominal discomfort
- diarrhea
- dysphagia
- GERD
- dry mouth
- thirst
- Musculoskeletal Neck pain/stiffness
- backache
- weakness
- joint symptoms
- arthritis
- myalgia
- muscle cramps
- Neurological Drowsiness/sedation
- anxiety
- sleep disturbances
- tremors
- syncope
- chills
- depression
- agitation
- confusion
- Respiratory Dyspnea
- lower respiratory infection
- Skin Rash/skin eruption
- pruritus
- erythema
- Urogenital Dysuria
- dysmenorrhea
Drug Interaction
Drug Interaction
| Drug Name | Risk Factors |
|---|---|
|
No interactions listed
|
-
|
Disease Interaction
Disease Interaction
| Disease Name | Risk Factors |
|---|---|
|
Current/History of Ischemic Cardiac, Cerebrovascular, or Peripheral Vascular Syndromes
|
Risk of serious cardiovascular events
|
|
Uncontrolled Hypertension
|
Risk of hypertensive crisis
|
Pregnancy
Pregnancy
Lactation
Special Use
Precaution
Overdose
Pharmacology
Storage
Details coming soon
Data Sources
Clinical & regulatory information on this page is compiled from the following government sources:
DISCLAIMER: This drug information content is provided for informational purposes only and is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Patients should always consult their physician with any questions regarding a medical condition and to obtain medical advice and treatment.