Medicine Overview
Adult Dose
| Clinical Information | Administration Information |
|---|---|
|
Indication: Vulvar and Vaginal Atrophy in Menopause Age: Adult |
Dose: Oral – 1-2 mg Frequency: by mouth once daily Duration: for 3 weeks, followed by 1 week off |
|
Indication: Prevention of osteoporosis |
Dose: Oral – 0.5 mg Frequency: by mouth once daily Duration: for 3 weeks, followed by 1 week off |
Child Dose
| Clinical Information | Administration Information |
|---|---|
|
Age: Pediatric |
Dose: No approved pediatric dosage available Note: No approved pediatric dosage available |
Administration
- May be taken with or without food
- Take at same time each day
Side Effect
- Anxiety
- Abdominal cramping
- Amenorrhea
- Bloating
- Breakthrough bleeding
- Breast enlargement
- Breast tenderness
- Delayed ejaculation
- Depression
- Dry mouth
- Headache
- Hypertension
- Impotency
- Influenza
- Leukorrhea
- Melasma
- Muscle cramps
- Nausea
- Nervousness
- Peripheral edema
- Polydipsia
- Pruritus
- Rash
- Swelling
- Spotting
- Syncope
- Toothache
- Vaginal discomfort
- vaginal erosion
- vaginal ulceration
- adherence of the vaginal ring to the vaginal wall (Estring)
- Vomiting
- Weight changes
Drug Interaction
Drug Interaction
| Drug Name | Risk Factors |
|---|---|
|
CYP1A2 and CYP3A4 inducers (e.g. aminoglutethimide, carbamazepine, phenobarbital, rifampin)
|
May decrease the effects of estradiol
|
|
Hydrocortisone, prednisolone
|
May enhance the effects when used together
|
Disease Interaction
Disease Interaction
| Disease Name | Risk Factors |
|---|---|
|
Undiagnosed Vaginal Bleeding
|
May mask serious conditions
|
|
Thrombophlebitis or Thromboembolic Disorders
|
Risk of blood clots
|
Pregnancy
Pregnancy
Lactation
Special Use
Precaution
Overdose
Pharmacology
Storage
Store in a cool (below 30°C) and dry place, away from light & children.
Data Sources
Clinical & regulatory information on this page is compiled from the following government sources:
DISCLAIMER: This drug information content is provided for informational purposes only and is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Patients should always consult their physician with any questions regarding a medical condition and to obtain medical advice and treatment.