Medicine Overview
Adult Dose
| Clinical Information | Administration Information |
|---|---|
|
Indication: Hyperthyroidism, Adjunct to radio-iodine therapy, Grave's disease, Preparation for thyroidectomy Age: Adult Condition: Initial |
Dose: Oral – 20-60 mg Frequency: daily as a single or divided dose Note: Reduced gradually once euthyroidism is achieved. |
|
Indication: Hyperthyroidism, Adjunct to radio-iodine therapy, Grave's disease, Preparation for thyroidectomy Age: Adult Condition: Maintenance |
Dose: Oral – 5-15 mg Frequency: daily Duration: at least 1 year or 18 months |
Child Dose
| Clinical Information | Administration Information |
|---|---|
|
Indication: Oral Hyperthyroidism; Adjunct to radio-iodine therapy; Preparation for thyroidectomy Age: 3-17 years |
Dose: Oral – 15 mg Frequency: daily Note: adjusted according to response; Duration of treatment: 18 to 24 months |
|
Indication: Oral Hyperthyroidism; Adjunct to radio-iodine therapy; Preparation for thyroidectomy Age: Neonates & Children below 12 years |
Dose: Oral – 250 micrograms/Kilogram/day Frequency: in divided doses |
Administration
- Can be taken with or without food
- Take at regular intervals
Side Effect
- Mild leucopaenia
- sore throat
- mouth ulcers
- fever
- bruising
- malaise
- rarely cholestatic jaundice
- nephrotic syndrome
- Nausea
- loss of taste
- headache
- arthralgia
- alopoecia
- Agranulocytosis
- aplastic anaemia
- hypoprothrombinaemia
- neutropaenia
- hypothyroidism and goitre
Drug Interaction
Drug Interaction
| Drug Name | Risk Factors |
|---|---|
|
Theophylline
|
Increased serum levels or toxicity
|
|
Anticoagulants (Warfarin, Heparin, Dabigatran, Rivaroxaban, Apixaban, Edoxaban)
|
May enhance effect
|
Disease Interaction
Disease Interaction
| Disease Name | Risk Factors |
|---|---|
|
Hyperthyroidism Due To Nodular Goitre
|
Can worsen thyroid dysfunction
|
Pregnancy
Pregnancy
Lactation
Special Use
Precaution
Overdose
Pharmacology
Storage
Store below 25° C.
Data Sources
Clinical & regulatory information on this page is compiled from the following government sources:
DISCLAIMER: This drug information content is provided for informational purposes only and is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Patients should always consult their physician with any questions regarding a medical condition and to obtain medical advice and treatment.