Medicine Overview
Adult Dose
| Clinical Information | Administration Information |
|---|---|
|
Indication: Hyperthyroidism Condition: Mild |
Dose: Oral – 15 mg/day Frequency: divided every 8 hours Note: initially |
|
Indication: Hyperthyroidism Condition: Moderate |
Dose: Oral – 30-40 mg/day Frequency: divided every 8 hours Note: initially |
Child Dose
| Clinical Information | Administration Information |
|---|---|
|
Indication: Hyperthyroidism Age: Child Condition: Initial |
Dose: Oral – 0.5-0.7 mg/kg/day Frequency: every day or divided every 8 hours Note: by mouth (oral); Not to exceed 30 mg/day |
|
Indication: Hyperthyroidism Age: Child Condition: Maintenance |
Dose: Oral – 0.2 mg/kg/day Frequency: every day or divided every 8 hours Note: by mouth (oral); Not to exceed 30 mg/day |
Administration
- Should be taken with food
- Take at same time each day
Side Effect
- Agranulocytosis
- Alopecia
- Aplastic anemia
- Dermatologic reactions (eg rash, pruritus, skin pigmentation)
- Hepatotoxicity
- Leukocytoclastic vasculitis
- Neuritis
- Polyarthritis
- Pruritus
- Salivary gland swelling
- Skin pigmentation
- Thrombocytopenia
- Urticaria
- Vertigo
Drug Interaction
Drug Interaction
| Drug Name | Risk Factors |
|---|---|
|
Beta-blockers (Propranolol, Metoprolol, Atenolol, Bisoprolol, Carvedilol, Nadolol, Timolol, Sotalol), cardiac glycosides, oral Anticoagulants (Warfarin, Heparin, Dabigatran, Rivaroxaban, Apixaban, Edoxaban) (e.g. warfarin), theophylline
|
May require dosage adjustments according to changes in patient's thyroid status
|
Disease Interaction
Disease Interaction
| Disease Name | Risk Factors |
|---|---|
|
No specific contraindications listed
|
Monitor for general drug reactions
|
Pregnancy
Pregnancy
Lactation
Special Use
Precaution
Overdose
Pharmacology
Storage
Store in a cool (below 30°C) and dry place, away from light and children.
Data Sources
Clinical & regulatory information on this page is compiled from the following government sources:
DISCLAIMER: This drug information content is provided for informational purposes only and is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Patients should always consult their physician with any questions regarding a medical condition and to obtain medical advice and treatment.