Medicine Overview
Adult Dose
| Clinical Information | Administration Information |
|---|---|
|
Indication: Chronic Obstructive Pulmonary Disease maintenance treatment of airflow obstruction including chronic bronchitis and/or emphysema |
Dose: Inhalations – 2 puffs Frequency: twice daily (morning and evening) Note: Do not exceed 2 inhalations twice daily |
|
Condition: Hepatic impairment |
Dose: Inhalations – Not specified Note: Studies not conducted. Since formoterol fumarate is predominantly cleared by hepatic metabolism, impairment may lead to plasma formoterol accumulation; monitor closely |
Child Dose
| Clinical Information | Administration Information |
|---|---|
|
Indication: Asthma maintenance Age: 12 years of age and older |
Dose: Oral inhalation – 160 mcg budesonide, 18 mcg glycopyrrolate, and 4.8 mcg formoterol fumarate per inhalation (total dose budesonide 320 mcg, glycopyrrolate 36 mcg, and formoterol 9.6 mcg) Frequency: Two inhalations twice daily Note: Route: Oral inhalation |
Renal Dose
| Clinical Information | Administration Information |
|---|---|
|
Condition: Renal impairment |
Dose: Not conducted Note: Studies not conducted |
|
Condition: Severe renal impairment (Creatinine Clearance less than 30 mL/min/1.73 m²) or end-stage renal disease requiring dialysis |
Dose: Use only if expected benefit outweighs the potential risk Note: Use only if expected benefit outweighs the potential risk |
Administration
- Shake well before use
- Use at same time each day
Side Effect
- Cough (4%)
- Urinary Tract Infection (UTI) (2.6%)
- Arthralgia (Less than 2%)
- Chest pain (Less than 2%)
- Tooth abscess (Less than 2%)
- Muscle spasms (Less than 2%)
- Headache (Less than 2%)
- Oropharyngeal pain (Less than 2%)
- Vomiting (Less than 2%)
- Pain in extremity (Less than 2%)
- Dizziness (Less than 2%)
- Anxiety (Less than 2%)
- Dry mouth (Less than 2%)
- Fall (Less than 2%)
- Influenza (Less than 2%)
- Fatigue (Less than 2%)
- Acute sinusitis (Less than 2%)
- Contusion (Less than 2%)
- Formoterol
- Hypersensitivity reactions
- Hyperglycemia
- Sleep disturbance
- Agitation
- Restlessness
- Tremor
- Nausea
- Tachycardia
- Palpitations
- Cardiac arrhythmias
Drug Interaction
Drug Interaction
| Drug Name | Risk Factors |
|---|---|
|
No interactions listed
|
-
|
Disease Interaction
Disease Interaction
| Disease Name | Risk Factors |
|---|---|
|
Asthma Without Long-Term Control Medication
|
Risk of severe asthma attacks
|
Pregnancy
Pregnancy
Lactation
Special Use
Precaution
Overdose
Pharmacology
Storage
Do not store above 30°C. Do not expose to temperatures higher than 50°C. Do not pierce the pressurized container. Keep out of the reach of the children.
Data Sources
Clinical & regulatory information on this page is compiled from the following government sources:
DISCLAIMER: This drug information content is provided for informational purposes only and is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Patients should always consult their physician with any questions regarding a medical condition and to obtain medical advice and treatment.