Medicine Overview
Adult Dose
| Clinical Information | Administration Information |
|---|---|
|
Indication: Overactive bladder Age: Adult |
Dose: Conventional tablet – 20 mg Frequency: twice daily Note: For the symptomatic treatment of urge urinary incontinence, urinary frequency and urgency. Reassess the need for continued therapy at regular intervals of 3-6 months. |
|
Indication: Overactive bladder Age: Adult |
Dose: Extended-release capsule – 60 mg Frequency: once daily in the morning Note: For the symptomatic treatment of urge urinary incontinence, urinary frequency and urgency. Reassess the need for continued therapy at regular intervals of 3-6 months. |
Child Dose
| Clinical Information | Administration Information |
|---|---|
|
Age: Child |
Dose: Form: Not specified Note: No approved pediatric dosage available |
Renal Dose
| Clinical Information | Administration Information |
|---|---|
|
Condition: Renal Impairment |
Dose: Conventional tablet – 20 mg Frequency: once daily or 20 mg on alternate days |
|
Condition: Renal Impairment |
Dose: Extended-release capsule – Not recommended Note: Not recommended for this creatinine clearance level |
Administration
- Take on empty stomach
- Take 1 hour before meals
Side Effect
- Dry mouth (20.1%)
- Constipation (9.6%)
- Tachycardia (Less than 2%)
- Headache (4.2%)
- Fatigue (1.9%)
- Rash (Less than 2%)
- Dyspepsia (1-2%)
- Abdominal pain (1-3%)
- Abdominal distention (Less than 2%)
- Constipation (9-10%)
- Dry eyes (1-2%)
- Dyspepsia (1-2%)
- Flatulence (1-2%)
- Urinary retention (Less than 1%)
- Urinary Tract Infection (UTI) (1-7%)
- Nasopharyngitis (3%)
- Nasal dryness (1%)
Drug Interaction
Drug Interaction
| Drug Name | Risk Factors |
|---|---|
|
Agents with anticholinergic action (e.g. amantadine, TCAs)
|
May potentiate effects
|
|
Drugs eliminated by active tubular secretion (e.g. procainamide, pancuronium, vancomycin, morphine, tenofovir)
|
May increase serum concentration of trospium chloride and/or the coadministered drug
|
Disease Interaction
Disease Interaction
| Disease Name | Risk Factors |
|---|---|
|
Urinary Retention, Gastric Retention
|
May worsen retention
|
|
Uncontrolled Angle-Closure Glaucoma
|
Risk of acute glaucoma
|
Pregnancy
Pregnancy
Lactation
Special Use
Precaution
Overdose
Pharmacology
Storage
Store at controlled room temperature 20°-25°C.
Data Sources
Clinical & regulatory information on this page is compiled from the following government sources:
DISCLAIMER: This drug information content is provided for informational purposes only and is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Patients should always consult their physician with any questions regarding a medical condition and to obtain medical advice and treatment.