Medicine Overview

Indication

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Adult Dose

Clinical InformationAdministration Information
Indication: Hypertension
Age: Adult
Dose: Tablet – 1 tablet
Frequency: once daily
Note: Preferably in the morning. Indicated as substitution therapy for treatment of essential hypertension in patients already controlled with indapamide and amlodipine given concurrently at the same dose level. The fixed dose combination is not suitable for initiation therapy.
Indication: Hypertension
Age: Adult
Condition: Severe hepatic impairment
Dose: Tablet
Note: Treatment is contraindicated.

Child Dose

Clinical InformationAdministration Information
Age: Pediatric
Dose: No approved pediatric dosage available
Note: No approved pediatric dosage available

Renal Dose

Clinical InformationAdministration Information
Condition: Renal impairment with severe renal impairment (creatinine clearance below 30 mL/min)
Dose: Not specified
Note: Treatment is contraindicated
Condition: Renal impairment with mild to moderate renal impairment
Dose: Not specified
Note: No dose adjustment is needed
Administration
  • May be taken with or without food
  • Take in morning
Side Effect

Drug Interaction

Drug NameRisk Factors
Lithium
Increased plasma lithium
Torsade de pointes-inducing drugs
Increased risk of ventricular arrhythmias

Disease Interaction

Disease NameRisk Factors
No specific contraindications listed
Monitor for general drug reactions

Pregnancy

Lactation
Special Use
Precaution
Overdose
Pharmacology
Storage

Details coming soon

Data Sources

Clinical & regulatory information on this page is compiled from the following government sources:

DISCLAIMER: This drug information content is provided for informational purposes only and is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Patients should always consult their physician with any questions regarding a medical condition and to obtain medical advice and treatment.