Medicine Overview
Adult Dose
| Clinical Information | Administration Information |
|---|---|
|
Indication: Hypertension Age: Adult |
Dose: Tablet – 1 tablet Frequency: once daily Note: Preferably in the morning. Indicated as substitution therapy for treatment of essential hypertension in patients already controlled with indapamide and amlodipine given concurrently at the same dose level. The fixed dose combination is not suitable for initiation therapy. |
|
Indication: Hypertension Age: Adult Condition: Severe hepatic impairment |
Dose: Tablet Note: Treatment is contraindicated. |
Child Dose
| Clinical Information | Administration Information |
|---|---|
|
Age: Pediatric |
Dose: No approved pediatric dosage available Note: No approved pediatric dosage available |
Renal Dose
| Clinical Information | Administration Information |
|---|---|
|
Condition: Renal impairment with severe renal impairment (creatinine clearance below 30 mL/min) |
Dose: Not specified Note: Treatment is contraindicated |
|
Condition: Renal impairment with mild to moderate renal impairment |
Dose: Not specified Note: No dose adjustment is needed |
Administration
- May be taken with or without food
- Take in morning
Side Effect
- Indapamide Hypokalaemia
- maculopapular rash
- Amlodipine Oedema
- Somnolence
- dizziness
- headache
- visual impairment
- diplopia
- palpitations
- flushing
- dyspnoea
- abdominal pain
- nausea
- dyspepsia
- changes of bowel habit
- diarrhoea
- constipation
- swelling ankle
- muscle spasms
- fatigue
- asthenia
Drug Interaction
Drug Interaction
| Drug Name | Risk Factors |
|---|---|
|
Lithium
|
Increased plasma lithium
|
|
Torsade de pointes-inducing drugs
|
Increased risk of ventricular arrhythmias
|
Disease Interaction
Disease Interaction
| Disease Name | Risk Factors |
|---|---|
|
No specific contraindications listed
|
Monitor for general drug reactions
|
Pregnancy
Pregnancy
Lactation
Special Use
Precaution
Overdose
Pharmacology
Storage
Details coming soon
Data Sources
Clinical & regulatory information on this page is compiled from the following government sources:
DISCLAIMER: This drug information content is provided for informational purposes only and is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Patients should always consult their physician with any questions regarding a medical condition and to obtain medical advice and treatment.