Medicine Overview

Indication

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Adult Dose

Clinical InformationAdministration Information
Indication: Adjunct to insulin therapy to improve blood sugar (glycemic) control
Age: Adults
Condition: Type 1 diabetes mellitus who have failed to achieve adequate glycemic control despite optimal insulin therapy
Dose: Oral Tablet – 200 mg
Frequency: once daily
Note: Recommended dose. Take before the first meal of the day.
Indication: Adjunct to insulin therapy to improve blood sugar (glycemic) control
Age: Adults
Condition: Type 1 diabetes mellitus who have failed to achieve adequate glycemic control despite optimal insulin therapy and tolerating 200 mg
Dose: Oral Tablet – 400 mg
Frequency: once daily
Note: The dose may be increased to 400 mg after at least three months if additional glycemic control is needed.

Child Dose

Clinical InformationAdministration Information
Age: Pediatric
Dose: No approved pediatric dosage available
Note: No approved pediatric dosage available

Renal Dose

Clinical InformationAdministration Information
Condition: Renal impairment
Dose: Tablet – Not recommended
Note: Initiation is not recommended when eGFR is less than 60 mL/min/1.73 m2. Assessment of renal function is recommended prior to initiation and periodically thereafter.
Condition: Persistent renal impairment
Dose: Tablet – Discontinue
Note: Should be discontinued if eGFR is persistently less than 45 mL/min/1.73 m2.
Administration
  • Take once daily before first meal
  • Take at same time each day
Side Effect

Drug Interaction

Drug NameRisk Factors
No interactions listed
-

Disease Interaction

Disease NameRisk Factors
No specific contraindications listed
Monitor for general drug reactions

Pregnancy

Lactation
Special Use
Precaution
Overdose
Pharmacology
Storage

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Data Sources

Clinical & regulatory information on this page is compiled from the following government sources:

DISCLAIMER: This drug information content is provided for informational purposes only and is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Patients should always consult their physician with any questions regarding a medical condition and to obtain medical advice and treatment.