For intravenous use only, anti-human T-lymphocyte immunoglobulin (rabbit) must be reconstituted with sterile water and then further diluted in 0.9% sodium chloride or 5% glucose to a concentration typically between 1 mg/mL and 4 mg/mL. The solution should be gently swirled and allowed to reach room temperature before administration through a high-flow central vein using an in-line filter. The first dose is infused over at least 6 hours, while subsequent doses require at least 4 hours. Premedication with corticosteroids, antihistamines, and antipyretics is recommended to reduce infusion-related reactions. Dosage should be halved if white blood cell counts fall between 2,000-3,000 cells/mm3 or platelets between 50,000-75,000 cells/mm3, and discontinuation considered if counts drop further. Monitoring for anaphylaxis is required during and for 24 hours post-infusion.

Details coming soon