Indication
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Medicine Overview
Adult Dose
| Clinical Information | Administration Information |
|---|---|
|
Indication: Parenteral nutrition Age: Adult Condition: Normal nutritional state or mild metabolic stress |
Dose: Parenteral nutrition – 0.10–0.15 g nitrogen/kg body weight/day (0.7–1.0 g amino acid/kg body weight/day) Frequency: daily Note: Corresponding requirements are 2.0–6.0 g for glucose and 1.0–2.0 g for fat. Total energy most often between 20–30 kcal/kg body weight/day. In obese patients, dose should be based on estimated ideal weight. |
|
Indication: Parenteral nutrition Age: Adult Condition: Moderate to high metabolic stress with or without malnutrition |
Dose: Parenteral nutrition – 0.15–0.30 g nitrogen/kg body weight/day (1.0–2.0 g amino acid/kg body weight/day) Frequency: daily Note: Corresponding requirements are 2.0–6.0 g for glucose and 1.0–2.0 g for fat. Total energy most often between 20–30 kcal/kg body weight/day. In obese patients, dose should be based on estimated ideal weight. |
Child Dose
| Clinical Information | Administration Information |
|---|---|
|
Indication: Parenteral nutrition Age: Children aged 2 years and above Condition: when oral or enteral nutrition is impossible, insufficient or contraindicated |
Dose: Parenteral nutrition – Dose not specified Note: For children aged 2 years and above when oral or enteral nutrition is impossible, insufficient or contraindicated |
Administration
Administer this triple-chamber parenteral nutrition emulsion exclusively via intravenous infusion into a central vein. Before administration, the vertical peel seals between the chambers must be broken by rolling the bag, and the contents mixed thoroughly by inverting the bag three times. The infusion rate should be individualized, generally not exceeding 2.6 ml/kg/hour for adults, typically administered over 12 to 24 hours. For pediatric patients aged 2 to 11 years, the rate should not exceed 2.4 ml/kg/hour. Monitor serum triglycerides, glucose, electrolytes, and liver function throughout therapy. Dosage adjustments are required for patients with renal or hepatic impairment, and use is contraindicated in patients with severe liver insufficiency or hypersensitivity to egg, soya, or peanut proteins. Protect from light when used in neonates and children under 2 years of age.
Side Effect
- The infusion may cause a rise in body temperature (incidence Less than 3%) and, less frequently, shivering, chills and nausea/vomiting (incidence Less than 1%). Transient increases in liver enzymes during intravenous nutrition have also been reported
- Thrombophlebitis is probably the most common adverse event in patients in general surgical wards
- The cause is in most cases due to infusions of saline, glucose or similar fluids and drugs
- Reports of other undesirable effects in conjunction with the included components are extremely rare
- Hypersensitivity reactions (anaphylactic reaction, skin rash, urticaria), respiratory symptoms (e.g. tachypnoea) and hyper/hypotension have been described. Haemolysis, reticulocytosis, abdominal pain, headache, tiredness and priapism have been reported
Drug Interaction
Drug Interaction
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Disease Interaction
Disease Interaction
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Pregnancy
Pregnancy
Lactation
Special Use
Precaution
Overdose
Pharmacology
Storage
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Data Sources
Clinical & regulatory information on this page is compiled from the following government sources:
DISCLAIMER: This drug information content is provided for informational purposes only and is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Patients should always consult their physician with any questions regarding a medical condition and to obtain medical advice and treatment.