Medicine Overview
Adult Dose
| Clinical Information | Administration Information |
|---|---|
|
Indication: Susceptible infections Age: Adult Condition: Susceptible infections |
Dose: Capsule – 50 mg/kg/day Frequency: four divided doses Note: Approximately one 250 mg capsule per each 4.5 kg (10 lbs) of body weight or one 500 mg capsule per each 9 kg (20 lbs) of body weight; administered by mouth |
|
Indication: Susceptible infections Age: Adult Condition: More severe infections |
Dose: Capsule – 100 mg/kg/day Frequency: four divided doses Note: Administered by mouth |
Child Dose
| Clinical Information | Administration Information |
|---|---|
|
Indication: Susceptible infections Age: Premature and full-term neonates |
Dose: Oral – 25 mg/kg/day Frequency: four divided doses Note: by mouth (oral) |
|
Indication: Susceptible infections Age: Full-term infants greater than 2 weeks |
Dose: Oral – 50 mg/kg/day Frequency: four divided doses Note: by mouth (oral) |
Renal Dose
| Clinical Information | Administration Information |
|---|---|
|
Condition: Renal impairment |
Dose: Not mentioned Note: Dose reduction may be required |
Administration
- Take on empty stomach
- Take 1 hour before or 2 hours after meals
Side Effect
- Nightmares
- Headache
- Rash
- Diarrhea
- Stomatitis
- Enterocolitis
- Nausea
- Vomiting
- Bone marrow suppression
- Aplastic anemia
- Peripheral neuropathy
- Optic neuritis
- Bone marrow suppression and irreversible aplastic anaemia
- Neutropenia
- thrombocytopenia
- Grey baby syndrome
- Rarely
- anaphylaxis
Drug Interaction
Drug Interaction
| Drug Name | Risk Factors |
|---|---|
|
Iron, Vitamin B12
|
Decreased effects in anemic patients
|
|
Phenobarbital, Rifampin
|
Reduce efficacy of chloramphenicol
|
Disease Interaction
Disease Interaction
| Disease Name | Risk Factors |
|---|---|
|
Porphyria
|
Can trigger acute attacks
|
|
Parenteral Admin For Minor Infections
|
Risk outweighs benefit
|
Pregnancy
Pregnancy
Lactation
Special Use
Precaution
Overdose
Pharmacology
Storage
Store in a cool dry place. Keep bottle securely closed. Protect from light.
Data Sources
Clinical & regulatory information on this page is compiled from the following government sources:
DISCLAIMER: This drug information content is provided for informational purposes only and is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Patients should always consult their physician with any questions regarding a medical condition and to obtain medical advice and treatment.