Medicine Overview
Adult Dose
| Clinical Information | Administration Information |
|---|---|
|
Indication: Treatment of women with severe acne, with associated symptoms of androgenization, including seborrhea and mild hirsutism Age: Adult |
Dose: Oral – 2 mg daily (with 35 mcg of ethinylestradiol daily) Frequency: once daily Duration: 21 days of the menstrual cycle Note: Start 1st treatment course on the 1st day of menstrual cycle; subsequent courses are started after 7 medication-free days following the preceding course. Withdraw treatment 3 or 4 cycles after the condition has resolved. Cyproterone Acetate + Ethinylestradiol should not be prescribed for the purpose of contraception alone. However, when taken as recommended Cyproterone Acetate + Ethinylestradiol will provide reliable contraception in patients treated for the above clinical conditions. |
Child Dose
| Clinical Information | Administration Information |
|---|---|
|
Age: Pediatric |
Dose: No approved dosage available Note: No approved pediatric dosage available |
Renal Dose
| Clinical Information | Administration Information |
|---|---|
|
Condition: Renal Impairment |
Dose: Cyproterone Acetate + Ethinylestradiol Note: Has not been specifically studied in renally impaired patients. Available data do not suggest a change in treatment in this patient population. |
Administration
- Take with food
- Take at same time daily
Side Effect
- Inhibits spermatogenesis
- reduces volume of ejaculate
- causes infertility
- produces abnormal spermatozoa
- gynecomastia and enlargement of mammary glands
- galactorrhoea and benign nodules
- Depressive mood changes
- Alterations in hair pattern
- skin reactions
- Fatigue and lassitude
- breathlessness
- weight changes
Drug Interaction
Drug Interaction
| Drug Name | Risk Factors |
|---|---|
|
Ketoconazole, Itraconazole, Clotrimazole, Ritonavir
|
Metabolism may be reduced
|
|
Rifampicin, Phenytoin
|
May reduce the levels of cyproterone
|
Disease Interaction
Disease Interaction
| Disease Name | Risk Factors |
|---|---|
|
Markedly Impaired Liver Function
|
Risk of liver toxicity
|
|
Dubin-Johnson Syndrome
|
Can worsen liver condition
|
Pregnancy
Pregnancy
Lactation
Special Use
Precaution
Overdose
Pharmacology
Storage
Store below 30°C and in dry place. Protect from light. Keep out of the reach of children.
Data Sources
Clinical & regulatory information on this page is compiled from the following government sources:
DISCLAIMER: This drug information content is provided for informational purposes only and is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Patients should always consult their physician with any questions regarding a medical condition and to obtain medical advice and treatment.