Medicine Overview

Indication

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Adult Dose

Clinical InformationAdministration Information
Indication: Acute migraine attacks
Age: Adult
Dose: Oral – Initially, 6.25-12.5 mg
Note: May repeat 2 hours later if needed. Maximum: 2 doses per 24 hours.

Child Dose

Clinical InformationAdministration Information
Indication: Migraine
Age: Child less than 12 years
Dose: Oral – Not established
Note: Safety and efficacy not established
Indication: Migraine
Age: Child greater than 12 years
Dose: Oral – 6.25-12.5 mg
Frequency: at onset of headache; may repeat once after 2 hours
Note: Not to exceed 25 mg/day; by mouth (oral)

Renal Dose

Clinical InformationAdministration Information
Condition: Renal Impairment
Dose: Not specified – 6.25 mg
Frequency: once
Note: Initially as a single dose. Maximum: 12.5 mg per 24 hours.
Administration
  • Take at first sign of migraine
  • Can take with or without food
Side Effect

Drug Interaction

Drug NameRisk Factors
SSRIs, Serotonin norepinephrine reuptake inhibitors
Increased risk of serotonin syndrome
Verapamil, Ketoconazole, Other potent CYP450 inhibitors
Increased plasma concentrations

Disease Interaction

Disease NameRisk Factors
Cardiovascular Disease
Risk of heart complications
Uncontrolled Hypertension
Risk of blood pressure crisis

Pregnancy

Lactation
Special Use
Precaution
Overdose
Pharmacology
Storage
Keep below 30° C temperature in a dry place. Protected from light. Do not freeze. Keep out of the reach of children.

Data Sources

Clinical & regulatory information on this page is compiled from the following government sources:

DISCLAIMER: This drug information content is provided for informational purposes only and is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Patients should always consult their physician with any questions regarding a medical condition and to obtain medical advice and treatment.