Medicine Overview
Adult Dose
| Clinical Information | Administration Information |
|---|---|
|
Indication: General Anesthesia Induction Age: Adult |
Dose: Intravenous Push – 0.3-0.6 mg/kg Duration: over 30-60 seconds |
Child Dose
| Clinical Information | Administration Information |
|---|---|
|
Indication: General Anesthesia Induction Age: less than 10 years |
Dose: Injection – Safety and efficacy not established Note: Safety and efficacy not established |
|
Indication: General Anesthesia Induction Age: greater than 10 years |
Dose: Intravenous push – 0.3-0.6 mg/kg Note: Intravenous push over 30-60 seconds |
Administration
- Must be administered by healthcare professional
- Inject over 30-60 seconds
Side Effect
- Transient injection site pain (30-80%)
- Skeletal muscle movements
- mainly myoclonic (32%)
- Opsoclonus (20%)
- Adrenal suppression
- Hiccups
- Apnea (duration 5-90 seconds)
- Arrhythmias
- Hyperventilation
- HTN
- Hypotension
- Hypoventilation
- Laryngospasm
- Nausea/vomiting
- Oxygen desaturation
- Snoring (may be associated with partial upper airway obstruction)
Drug Interaction
Drug Interaction
| Drug Name | Risk Factors |
|---|---|
|
Antipsychotics (Haloperidol, Risperidone, Quetiapine, Olanzapine, Clozapine, Aripiprazole), Sedatives, Opioids, Calcium-channel blockers
|
Interaction not specified
|
Disease Interaction
Disease Interaction
| Disease Name | Risk Factors |
|---|---|
|
Reduced Adrenocortical Function
|
Can suppress adrenal function
|
|
Porphyria
|
Can trigger acute attacks
|
Pregnancy
Pregnancy
Lactation
Special Use
Precaution
Overdose
Pharmacology
Storage
Details coming soon
Data Sources
Clinical & regulatory information on this page is compiled from the following government sources:
DISCLAIMER: This drug information content is provided for informational purposes only and is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Patients should always consult their physician with any questions regarding a medical condition and to obtain medical advice and treatment.