Medicine Overview
Adult Dose
| Clinical Information | Administration Information |
|---|---|
|
Indication: Depression/Anxiety Age: Adult |
Dose: Oral – Initiate at low dose (25 mg/day) Frequency: gradually titrate upward every 5-7 days Note: Dosage range: 25-300 mg/day by mouth, up to 150 mg/day as single dose. If dose exceeds 150 mg/day, divide every 12 hours. |
|
Indication: Depression/Anxiety Age: Adult Condition: Hepatic impairment |
Dose: Oral – Lower dose Note: Adjust gradually for depression. |
Child Dose
| Clinical Information | Administration Information |
|---|---|
|
Age: less than 12 years old |
Dose: Not recommended Note: Not recommended |
Administration
- May take with or without food
- Take at bedtime
Side Effect
- Sedation
- fatigue
- weakness
- lethargy
- Dry mouth
- Constipation
- Blurred vision
- Headache
- Agitation
- Insomnia
- Anxiety
- Nausea
- vomiting
- Sweating
- Confusion
- extrapyramidal symptoms (EPS)
- dizziness
- paresthesia
- Orthostatic hypotension
- ECG changes
- tachycardia
- Increased LFTs
- Tinnitus
- Sexual dysfunction
- Rash
- Seizure
- Agranulocytosis
- Thrombocytopenia
- Eosinophilia
- Leukopenia
- SIADH
Drug Interaction
Drug Interaction
| Drug Name | Risk Factors |
|---|---|
|
Methylphenidate
|
May increase plasma doxepin levels
|
|
Sympathomimetics (Ephedrine, Pseudoephedrine, Phenylephrine)
|
Potentiates hypertensive action
|
Disease Interaction
Disease Interaction
| Disease Name | Risk Factors |
|---|---|
|
Mania
|
Can trigger manic episode
|
|
Glaucoma
|
Can increase eye pressure
|
Pregnancy
Pregnancy
Lactation
Special Use
Precaution
Overdose
Pharmacology
Storage
Store at 15-30°C.
Data Sources
Clinical & regulatory information on this page is compiled from the following government sources:
DISCLAIMER: This drug information content is provided for informational purposes only and is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Patients should always consult their physician with any questions regarding a medical condition and to obtain medical advice and treatment.