Medicine Overview

Indication

Know Medicine, Follow Guideline

Adult Dose

Clinical InformationAdministration Information
Indication: HIV infection
Age: Adult
Condition: Combined with other antiretrovirals
Dose: Oral – 600 mg
Frequency: once daily
Note: Dosing at bedtime recommended during 1st 2-4 weeks of therapy to improve tolerability.
Indication: HIV infection
Age: Adult
Condition: Mild (Child-Pugh Class A) hepatic impairment
Dose: Oral – 600 mg
Frequency: once daily
Note: Dose adjustment not necessary; use caution.

Child Dose

Clinical InformationAdministration Information
Indication: HIV infection
Age: greater than 3 years
Condition: Combined with other antiretrovirals
Dose: Oral – 200 mg
Frequency: once daily
Indication: HIV infection
Age: greater than 3 years
Condition: Combined with other antiretrovirals
Dose: Oral – 250 mg
Frequency: once daily

Renal Dose

Clinical InformationAdministration Information
Condition: Renal impairment
Dose: Renal impairment – No dosage adjustment needed
Note: Renal impairment: No dosage adjustment needed
Administration
  • Take on empty stomach
  • Take at bedtime
Side Effect

Drug Interaction

Drug NameRisk Factors
Hormonal contraceptives
Interaction
Rifampicin, Rifabutin, Clarithromycin
Interaction with antibacterials

Disease Interaction

Disease NameRisk Factors
Severe Hepatic Impairment
Can worsen liver function

Pregnancy

Lactation
Special Use
Precaution
Overdose
Pharmacology
Storage
Store at 25°C.

Data Sources

Clinical & regulatory information on this page is compiled from the following government sources:

DISCLAIMER: This drug information content is provided for informational purposes only and is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Patients should always consult their physician with any questions regarding a medical condition and to obtain medical advice and treatment.